2.5.2 Hypothalamus-Pituitary Clinical Cases

Question 1

Patient presents with large wide feet. What is your diagnosis?

Answer 1

Acromegaly

Question 2

What is the best test for acromegaly?

Answer 2

IGF-1 (Somatomedin)

Question 3

What is a pituitary apoplexy?

Answer 3

Abrupt acute hemorrhagic infarction of the pituitary

Question 4

How would you treat a patient with diabetes insipidus?

Answer 4

Question 5

What is the pathogeesis of acromegaly?

Answer 5

Pituitary adenoma

40% have gsp mutation

Question 7

What are some clinical manifestations of acromegaly?

Answer 7

Cardiac manifestations - LVH and HTN

CI - Colon polyps and GI malig

Question 8

How do you treat pituitary apoplexy?

Answer 8

Corticosteroids and surgical decompression if necessary

Question 9

What is the main treatment for acromegaly?

Answer 9

Question 10

What could account for:

Sudden headache

Loss of vision

Several month history of fatigue, decreased libido and ED

Answer 10

Pituitary tumor

Hypopituitarism

Pituitary apoplexy

Question 11

What is this an image of?

Answer 11

Abnormality of pituitary

Question 12

How will a pituitary apoplexy present in clinic?

Answer 12

Question 13

When approaching a patient with polyuria what are the main concerns?

Answer 13

Question 14

What therapy would you use in adrenal insufficiency?

Answer 14

Question 15

What therapy would you use for addison’s disease?

Answer 15

Question 16

What is the pathophysiology of pituitary apoplexy?›

Answer 16

Question 17

What are the urine characteristics in a patient with diabetes insipidus?

Answer 17