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Renal and Endocrine > 3.4.3 Diabetes Mellitus and Treatment > Flashcards

3.4.3 Diabetes Mellitus and Treatment Flashcards

1
Q

What are the effects of GLP-1?

A
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2
Q

What is the treatment algorithm for type 2 DM?

A
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3
Q

What are the treatment goals of Type I DM?

A
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4
Q

What are some of the different insulin preparations?

A
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5
Q

What are some of the symptroms of hypoglycemia?

A
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6
Q

What treatment method is on the horizon for Type 1 DM?

A

Closed loop pumps

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7
Q

What is the mainstay for the treatment of Type 1 DM?

A

Insulin injection

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8
Q

What are the four types of neuropathy possible in DM patients?

A

Peripheral, autonomic, proximal, focal

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9
Q

What are some of the oral anti-hyerglycemics and their attributes

A
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10
Q

What two lifestyle changes help in the preservation of islet beta cells?

A

Diet and Excercise

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11
Q

What are the treatment goals of type 2 DM?

A
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12
Q

What is the progression of treatment of Type 2 DM?

A
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13
Q

How do thiazolidinediones decrease insulin resistance?

A

Make muscle and adipose cells more sensitive to insulin

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14
Q

What are two retinopathies associated with DM?

A

Proliferative retinopathy, macular edema

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15
Q

What type of DM predisposes patients to hyperosmolar hyperglycemic state?

A

Type II DM

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16
Q

Identify the drugs in these classes?

A
17
Q

What is the normal insulin excretion style?

A

Pulsatile

18
Q

What is increased by sulfonylurea?

A

Endogenous insulin secretion

19
Q

What are some of the future changes in the treatment of DM?

A

Preservation/regeneration of islet cells

Stop immune destruction

Islet cell transplantation

Closed loop insulin pumps

Better insulin

Stop obesity

20
Q

What are some of the Type 1 DM management goals?

A

Normalize glucose, BP and lipid management to reduve CVD

21
Q

What type of DM predisposes patients to DKA?

A

Type I DM

22
Q

What is the function of the enzymes that are blocked by alpha-glucocidase inhibitors?

A

Digest starches in the small intestine

23
Q

What are some of the complications of DM?

A

Atherosclerosis, retinopathy, neuropathy, nephropathy, hypoglycemia unawareness, diabetic foot, DKA, hyperosmolar nonketotic coma, HOHG

24
Q

How does Ashley feel about this lecture?

A

Unamused

Renal and Endocrine (46 decks)

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