Liver Flashcards
Function
Bile secretion
Converts bilirubin to bile
Glycogen storage
Location
RUQ
Protected by ribs 7-11
Location changes with breathing
Liver lobes (4)
right lobe
left lobe
quadrate - lies next to GB, more anterior and inferior
caudate - more posterior and superior
Liver segments (8)
Named by number
Clockwise direction
Portal triad
Found in the free edge of the lesser momentum
Hepatic artery
Hepatic portal vein
Common bile duct
Blood supply to liver
Dual blood supply :-
R & L hepatic artery
HPV
Hepatic portal system
Venous drainage of liver
HPV drains blood from foregut, midgut and hindgut to the liver for cleaning
Hepatic veins drain blood from the liver to the IVC then into the RA
HPV
Splenic vein + SMV
Anatomical relations
Inferior to the right semi-diaphragm
GM - posterior and inferior
Structure
Blood passes through sinusoids towards central vein
Hepatocytes clean the blood
Central vein contains cleaned blood and drains it to hepatic veins
Pathology
Injury
Inflammatory response
Fibrosis, scarring
Cirrhosis
Metabolic functions
Carb metabolism - gluconeogenesis, glycogenolysis
Fat metabolism - lipoproteins, cholesterol, phospholipids
Protein metabolism
Hormone metabolism
Vitamin storage - vit A
Liver stores around 10 months worth
Vitamin storage - vit D
Liver stores around 3 weeks worth
Vitamin storage - vit B12
Liver stores years worth
