Chronic liver disease Flashcards

1
Q

Duration

A

Greater than 6 months

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2
Q

What is it?

A

Progressive destruction and regeneration of the liver parenchyma leading to fibrosis and cirrhosis

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3
Q

Causes

A
Alcohol
NAFLD
Vital hepatitis 
Autoimmune liver disease - PBC, PSC, autoimmune hepatitis
Haemochromatosis 
Wilsons disease 
alpha 1 antitrypsin 
budd chiari
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4
Q

Disease progression

A
Causes 
Recurrent inflammation
Fibrosis
Compensated cirrhosis
Decompensated cirrhosis
Liver failure
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5
Q

Investigations

A

Albumin - decreased

Prothrombin time - increased

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