NME 2.6 Flashcards
1
Q
what does the portal triad include?
A
- portal vein
- hepatic artery
- bile duct
2
Q
what are the four cell types in the liver?
A
- stellate cell
- hepatocyte
- kupffer cell
- sinosoid endothelial cell
3
Q
what are kupffer and stellate cell for?
A
immunological
4
Q
what is space of disse?
A
- space between the endothelial cell
- hepatocyte will bath with blood for metabolic function
5
Q
what is the acinar model of the hepatic acinus?
A
- diamond shape
- terminal hepatic venules at either point
- hepatocytes divide into three zones
6
Q
what are the zones for the acinar model?
A
- outer zone
- middle zone
- inner zone
7
Q
what is at the outer zone?
A
- portal triad
- high oxygen and nutrients
- rapid glycogen synthesis
- high plasma protein synthesis
- closest to hepative triad
8
Q
what is at the middle zone?
A
- intermediate
9
Q
what is at the inner zone?
A
- low oxygen
- high metabolic waste
- main site of alcohol detoxification
- most vulnerable to damage
- closest to central vein
10
Q
what are hepatocytes?
A
- epithelial cells of liver
- linked by plate arragement
- cytoplasmic glycogen store
- cell surface in contact with bile canaliculi
11
Q
function of hepatocytes?
A
- depends on location
- hepatocytes close to portal triad is for glycogen and glucose metabolism and protection and secretion of plasma proteins
- hepatocytes close to central vein is for detoxification
- bile secretion
- regulation of plasma lipid levels
12
Q
what are kupffer cells?
A
- phagocytes
13
Q
what are stellate cells?
A
- pericytes
- immune function
- absorb fat
- store vitamin A
