NME 2.31 Flashcards

1
Q

describe link reaction during high cellular energy?

A
  • PDh kinase will inhibit PDH

- reduce conversion of pyruvate to acetyl CoA

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2
Q

describe link reaction during low cellular energy?

A
  • PDH phosphatase will stimulate PDH

- increase conversion of pyruvate to acetyl CoA

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3
Q

function of kreb cycle?

A
  • provides ATP

- provides reduced NAD and FAD for energy generation

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4
Q

what happens to kreb cycle when there is high cellular energy?

A

reduce kreb cycle

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5
Q

what happens to kreb cycle when there is low cellular energy?

A

increase kreb cycle

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6
Q

how many ATP does glycolysis produce?

A
  • 2 ATP
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7
Q

how many ATP does link reaction produce?

A

zero

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8
Q

how many ATPs does kreb cycle produce?

A

2 atp

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9
Q

how many ATP does electron transport chain produce?

A
  • 28 ATP
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10
Q

where does electron transport chain occur?

A
  • inner membrane of mitochondria
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11
Q

describe electron transport chain?

A
  • 5 proteins lined up and electrons pass through

- as electron pass through help movement of protons into the intermembrane space

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12
Q

which complex are electrons from NADH moved to?

A

complex I or NADH dehydrogenase

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13
Q

which complex are electrons from FADH2 moved to?

A

complex 2 or succinate dehydrogenase

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14
Q

why is complex V important?

A

produce ATP

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15
Q

what is Coenzyme Q for?

A
  • involved in electrons from complex II and III
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16
Q

what is cytochrome c for?

A
  • involved in moveing electrons from complex III and IV
17
Q

what is complex IV called?

A

cytochrome c oxidase

18
Q

chat is complex V called?

A
  • atp synthase
19
Q

how does ATP synthase produce ATP?

A
  • as protons moved into intermembrane space

- high concentrationa nd diffuse back in and cause rotation of the ATP synthase and produce ATP

20
Q

what is the importance of oxygen?

A
  • oxygen is last electron acceptor
  • oxygen needed for kreb cycle
  • oxygen needed for electron transport chain
  • NADH and FADH2 can no longer release electrons without oxygen
21
Q

what does carbon monoxide and cyanide stop?

A
  • since oxygen is last electron acceptor

- inhibit transfer of electrons from complex IV

22
Q

what does oligomycin do?

A
  • inhibit ATP synthase
23
Q

what does dinitrophenol do?

A
  • uncoupling chemical

- cease ATP production

24
Q

what does uncoupling chemical mean?

A
  • create proton leak
25
Q

what is complex III called?

A

cytochrome bc-1