Lung Cancer

Question 1

what are the different types of lung cancer

Answer 1

small cell lung cancer

non-small cell lung cancer

Question 2

what is SCLC

Answer 2

malignant epithelial tumour from cells lining the lower respiratory tract

Question 3

epi

Answer 3

very common cause of death
men>women
associated with smoking

Question 4

aetiology

Answer 4

smoking

Question 5

how does smoking cause lung cancer

Answer 5

smoke contains carcinogens

Question 6

how common is SCLC

Answer 6

accounts for 15% of lung cancers

Question 7

is SCLC or NSCLS more associated with smoking

Answer 7

SCLC

Question 8

where do SCLCs commonly arise

Answer 8

central lung with mediastinal involvement

Question 9

how aggressive is SCLC

Answer 9

very aggressive malignancy

Question 10

risk factors

Answer 10

smoking

passive smoking

Question 11

what are features of lung cancer

Answer 11

patient is commonly elderly + male

cough
dyspnoea
haemoptysis
chest pain
weight loss + change in appetite

Question 12

which lung cancer is clubbing and hypertrophic pulmonary osteoarthroscopy (fat fingers) more common in

Answer 12

NSCLC

Question 13

investigations

Answer 13

1 CXR PA
-first line
2 CT chest, liver, adrenals for metastasis
-if abnormality on CXR or concerning symptoms
3 sputum cytology
-for pathological confirmation with malignant cells in sputum

Question 14

what are common sites of metastasis in lung cancer

Answer 14

BLAB

Brain
Liver
Adrenals
Bone

Question 15

what is the first line investigation in suspected lung cancer

Answer 15

CXR

Question 16

def of NSCLC

Answer 16

malignant epithelial tumours of cells lining lower respiratory tract

Question 17

how common is NSCLC

Answer 17

makes up 85% of lung cancer

Question 18

what are the 3 main types of NSCLC

Answer 18

adenocarcinoma
squamous cell carcinoma
large cell carcionoma

Question 19

what is the most common form of NSCLC

Answer 19

adenocarcinoma

Question 20

where are adenocarcinomas commonly found in the lungs

Answer 20

peripheries

Question 21

what is the second most common form of NSCLC

Answer 21

squamous cell carcinoma

Question 22

where are squamous cell carcinomas commonly found in the lungs

Answer 22

central airways

Question 23

what is the least common form of NSCLC

Answer 23

large cell carcinoma

Question 24

where are large cell carcinomas commonly found in the lungs

Answer 24

centrally

Question 25

what condition is associated with NSCLC

Answer 25

COPD

Question 26

what ct scan is used in investigation of NSCLC

Answer 26

contrast enhanced CT scan of neck thorax and abdomen

completed with abnormality detected on CXR or worrying symptoms

Question 27

what is neuro specific enolase associated with

Answer 27

SCLC

Question 28

what is ALK (anaplastic lymphoma lipase) associated with

Answer 28

NSCLC