Oesophageal Cancer Flashcards
1
Q
def
A
majority of oesophageal cancers are mucosal lesions which originate in the epithelial cells lining the oesphagus
2
Q
what are two different types of oesophageal cancer
A
squamous cell carcinoma
adenocarcinoma
3
Q
where are squamous cell carcinomas found
A
upper 2/3s
4
Q
where are adenocarcinomas found
A
lower 1/3
5
Q
what causes squamous cell carcinomas
A
alcohol and tobacco
HPV
6
Q
what causes adenocarcinoma
A
barretts oesophagus + GORD
obesity
males
poor diet
7
Q
what are risk factors for oesophageal carcinoma
A
ABCDEFGH
Achalasia, ASH (alcohol, smoking, h pylori) Barretts + GORD (A) Corrosive oesophagitits Diverticulitis Eosophageal Web Familial Genetic Hiatus hernia (A)
8
Q
what are features of oesophageal cancer
A
dysphagia + odynophagia
weight loss
9
Q
what does dysphagia indicate in OC
A
poor prognosis
as already blocking 2/3 of lumen
10
Q
what is the first line investigation for OC
A
OGD with biopsy
