6: Nutrition in Humans Flashcards

1
Q

Which processes does nutrition in humans consist of?

A
  1. Ingestion: Food is taken in through the mouth.
  2. Digestion: Food is broken down into soluble and simple molecules.
  3. Absorption: The soluble and simple food molecules enter the circulatory system.
  4. Assimilation: The absorbed food molecules are taken up by cells for metabolism.
  5. Egestion: The undigested and unabsorbed materials are removed from the body as faeces.
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2
Q

Where does nutrition in humans take place?

A

Nutrition in humans take place in the digestive system, which consists off the alimentary canal and its associated digestive glands.

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3
Q

What are the organs in the alimentary canal?

A

The alimentary canal is a long tube starting from the mouth cavity, which leads to the pharynx, the oesophagus, the stomach, the small intestine (duodenum and ileum), and the large intestine (caecum, colon, and rectum). It ends at the anus.

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4
Q

List three organs that produce digestive juices to the alimentary canal.

A

Digestive glands: salivary glands, pancreas, liver

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5
Q

What is the name of the process of chewing food into small pieces?

A

Mastication

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6
Q

What are the types of human teeth?

A

We have 4 types of teeth: incisors, canines, premolars, and molars.

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7
Q

What are the shape and function of incisors?

A

Incisors are chisel-shaped with flat sharp edges. They have one root. They are used for biting the cutting food.

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8
Q

What are the shape and function of canines?

A

Canines are pointed and curved. They have one root. They are used for tearing flesh.

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9
Q

What are the shape and function of premolars?

A

Premolars have broad top with cusps. They have one or two roots. They are used for crushing and grinding food.

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10
Q

What are the shape and function of molars?

A

Molars have a similar shape to premolars. They have larger broad tops and larger cusps. They have two or three roots. They are used for crushing and grinding food.

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11
Q

What is dentition?

A

Dentition refers to the numbers and arrangement of different types of teeth in a mammal. It can be represented by a dental formula.

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12
Q

What does the dental formula describe?

A

The dental formula shows the numbers and types of teeth on each side of the upper and lower jaws.

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13
Q

What is the dental formula for adults?

A

2123/2123

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14
Q

How many teeth are there in a complete set of milk teeth, and how can it be represented with the dental formula?

A

There are 20 teeth in a complete set of milk teeth. There is no premolar and there are only 2 molars on each side. The dental formula is 2102/2102.

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15
Q

What are three regions that a tooth is divided into?

A

Crown, neck, and root. The crown is the region visible above the gum. The neck is the region surrounded by the gum, and the toot is the region embedded in the jaw bone.

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16
Q

What are three layers that each tooth consists of?

A

Enamel, dentine, and pulp cavity.

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17
Q

What are the features of enamel?

A

Enamel is the outermost, hardest part of the crown. It is the hardest tissue in our body. It is non-living and is made mainly of calcium salts. It protects the tooth from wearing down as a result of chewing.
Around the roots, the enamel is replaced by cement. Fibres from the cement pass into the jawbone, forming the periodontal membrane. The cement and periodontal membrane fix the tooth to the jawbone.

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18
Q

What are the features of dentine?

A

Dentine is the middle region of the tooth. It is a bone-like substance, but is not as hard as enamel.
There are strands of living cytoplasm running through the dentine.

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19
Q

What are the features of the pulp cavity?

A

The pulp cavity contains living cells, blood vessels, and nerve fibres. The blood vessels supply oxygen and nutrients to the tooth, and remove wastes from it. The nerve fibres can detect temperature and pressure/pain.

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20
Q

Give two examples of common dental diseases.

A

Tooth decay and periodontal disease.

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21
Q

How is tooth decay developed?

A

Tooth decay starts with the formation of plaque, which consists of food debris and bacteria, on tooth surfaces.
Bacteria in the plaque act on the food debris to produce acids. The acids dissolve the enamel and make holes on the tooth.

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22
Q

How is periodontal disease developed?

A

Periodontal disease starts with the formation of plaque, which consists of food debris and bacteria, on tooth surfaces. The plaque accumulates between the teeth and gums. The bacteria in the plaque produce toxins which cause inflammation of the gums. The gums become red, swollen and can bleed easily. If the inflammation is not treated, the toxins start to break down the cement, the periodontal membranes, and the jawbone. The teeth may eventually become loose and fall out.

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23
Q

Why is digestion necessary?

A

Among the seven types of food substances taken into our body, starch and most proteins and lipids are large, complex molecules. Since the wall of the alimentary canal is differentially permeable, the food molecules must be broken down into simple, small, and soluble molecules so that they can pass through the wall and enter the blood. The process of breaking down food into small molecules is called digestion.

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24
Q

Give three examples of substances that a can be absorbed into the blood directly without undergoing digestion.

A

Water, vitamins, and minerals

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25
Q

How can the digestion processes in our body be classified?

A

It can be classified into two types: physical digestion and chemical digestion.

26
Q

What is physical digestion?

A

Physical digestion is the breaking down of food into smaller pieces by physical actions. It increases the surface area of food in contact with the digestive juices, but it does not change the chemical structure of the food.
After physical digestion, the resultant food pieces are not yet small enough for absorption. They must be further broken down into smaller molecules by chemical digestion.

27
Q

Give 4 examples of physical digestion.

A

Mechanical actions of the alimentary canal, including
1. chewing in the mouth cavity (mastication)
2. churning in the stomach
3. peristalsis along the alimentary canal.
Emulsification of lipids by bile salts in the small intestine.

28
Q

What is chemical digestion?

A

Chemical digestion involves chemical reactions in which large, complex food molecules are broken down into small, simpler forms. The reactions are catalysed by digestive enzymes.

29
Q

How can we classify digestive enzymes in our digestive system?

A

We can classify them into three main types:
1. carbohydrates, which break down complex carbohydrates into simpler sugars
2. proteases, which break down proteins into polypeptides, peptides and amino acids
3. lipases, which break down lipids into fatty acids and glycerol.

30
Q

What kinds of digestion take place in the mouth cavity?

A

In the mouth cavity, food is chewed into small pieces by teeth and mixed with saliva, a digestive juice produced by the salivary glands. After chewing, the tongue rolls the food into a soft mass called a bolus. The bolus is then swallowed down the oesophagus through the pharynx.

31
Q

What are the components of saliva?

A
  1. Salivary amylase: It is a kind of carbohydrase. It catalyses the breakdown of starch into maltose. It works best in a slightly alkaline medium.
  2. Mucus: It is a sticky material that helps bind food particles together. It moistens and lubricates the food, making the food easier to be swallowed.
  3. Water: It dissolves soluble substances in the food.
32
Q

How does the bolus move through the pharynx to the oesophagus?

A

The pharynx leads to both the oesophagus and the trachea. To ensure that the bolus passes into the oesophagus, and not into the trachea and the nasal cavity, a series of events takes place during swallowing:
1. The tongue rises to push the bolus towards the pharynx.
2. The soft palate moves up to prevent the bolus from entering the nasal cavity.
3. The larynx rises so that the epiglottis covers the opening to the trachea. This prevents the bolus from entering the trachea.
4. The bolus enters the oesophagus.

33
Q

What is peristalsis?

A

Peristalsis is the wave-like movement of the wall of the alimentary canal. It is produced by the alternate contraction and relaxation of the longitudinal muscles and circular muscles in the wall of the alimentary canal.

34
Q

How is the bolus pushed down the oesophagus to the stomach by peristalsis?

A

Behind the bolus: circular muscles contract, longitudinal muscles relax, the lumen becomes smaller. The food is squeezed forward.
In front of the bolus: circular muscles relax, longitudinal muscles contract. The food slides through the lumen.

35
Q

What is the importance of peristalsis?

A
  1. It pushes food along the oesophagus and other parts of the alimentary canal.
  2. It helps mix the food with digestive juices.
  3. It increases the contact between the wall of the alimentary canal and digested food to facilitate absorption.
36
Q

What are the names of the rings of muscles guarding the entrance and exit of the stomach respectively?

A

Cardiac sphincter: guards the entrance of the stomach
pyloric sphincter: guards the exit of the stomach

37
Q

What is the importance of the cardiac sphincter and the pyloric sphincter?

A

Contraction of the cardiac sphincter prevents food from flowing back into the oesophagus. Meanwhile, the pyloric sphincter controls the release of food into the duodenum. This allows the food to stay in then stomach for a sufficiently long period of time for digestion.

38
Q

What kinds of digestion takes place in the stomach?

A

Gastric juice secreted by gastric glands on the stomach wall digest the food chemically. Muscles in the stomach lining contract to churn the food into a creamy liquid called chyme, digesting the food physically. The chyme is then released into the duodenum.

39
Q

What are the components of gastric juice?

A
  1. Pepsin: It is a kind of protease. It catalyses the breakdown of proteins into peptides. It works best in an acidic medium of about pH 2.
  2. Hydrochloric acid: It provides an acidic medium for the action of pepsin. It kills most bacteria in food.
  3. Mucus: It protects the stomach wall from being digested by the pepsin and being damaged by the hydrochloric acid.
40
Q

What is the cause of gastric ulcer?

A

A kind of bacteria called Helicobacter pylori

41
Q

What kinds of digestion take place in the small intestine?

A

The chyme from the stomach contains partly digested food. The digestion of food is completed in the small intestine, which includes the duodenum and ileum. In the small intestine, food is chemically digested by pancreatic juice and intestinal juice. It is also physically digested by bile secreted by the liver.

42
Q

What are the features and components of bile?

A

Bile is a green alkaline fluid produced by the liver. It is temporarily stored in the gall bladder and is released through the bile duct into the duodenum. It contains no digestive enzyme. It contains three substances:
1. Bile salts: They emulsify lipids into small droplets. This facilitates chemical digestion by increasing the surface area of lipids for lipase to act on.
2. Bile pigments: They are formed from the breakdown of haemoglobin from red blood cells. They are waste products and do not take part in digestion.
3. Sodium hydrogencarbonate: It is alkaline. It neutralises the acidic chyme and provides an alkaline medium for the action of enzymes in the small intestine.

43
Q

What are the features and components of pancreatic juice?

A

Pancreatic juice is produced by the pancreas. It is carried along the pancreatic duct to the duodenum. It contains four substances:
1. Pancreatic amylase: It catalyses the breakdown of the remaining starch (not digested in the mouth cavity) into maltose.
2. Proteases: They catalyse the breakdown of some proteins into peptides, and some peptides into amino acids.
3. Pancreatic lipase: It catalyses the breakdown of the emulsified lipids into fatty acids and glycerol.
4. Sodium hydrogencarbonate: It is alkaline. It neutralises the acidic chyme and provides an alkaline medium for the action of enzymes in the small intestine.

44
Q

What are the features and components of intestinal juice?

A

Intestinal juice is produced by some glands in the wall of the small intestine. It is slightly alkaline and mainly consists of water, mucus, and sodium hydrogencarbonate. It provides an alkaline medium for the action of enzymes.
The epithelium of the small intestine has specialised cells that have various enzymes on their cell membranes. They include carbohydrases which catalyse the breakdown of disaccharides into monosaccharides, and proteases which catalyse the breakdown of some peptides into amino acids.

45
Q

Give two examples of carbohydrases that catalyse the breakdown of disaccharides into monosaccharides.

A

Maltase, which catalyses the breakdown of maltose into glucose.
Sucrase, which catalyses the breakdown of sucrose into glucose and fructose.

46
Q

Where does absorption of food molecules mainly take place?

A

Absorption of food molecules mainly takes place in the ileum (small intestine).

47
Q

In what ways is the small intestine adapted for absorption?

A
  1. Our small intestine is very long; it is about 7m long in adults. This allows sufficient time for complete digestion snd absorption.
  2. The inner wall of the small intestine is highly folded and there are many finger-like projections called villi.
  3. Peristalsis of the small intestine brings newly digested food molecules into close contact with the villi for absorption. This also helps keep a steep concentration gradient of food molecules across the wall of the small intestine to increase the rate of diffusion of food molecules.
48
Q

How do the structural features of villi help it adapt for absorption?

A
  1. Villi are finger-like projections. This increases the surface area for absorption.
  2. The epithelium of the villi is very thin, being only one-cell thick. This provides a short distance for diffusion of food molecules into the blood. Absorption can take place rapidly.
  3. The cell membrane of the epethelial cells of the villi has a large number of microvilli/brush borders. This further increases the surface area our absorption.
  4. Each villus has a lymph vessel called lacteal in the centre. The lacteal is surrounded by a network of capillaries. These allow the absorbed food molecules to be carried away rapidly. A steep concentration gradient of for molecules is kept across the wall of the small intestine to increase the rate of diffusion of food molecules.
49
Q

How is digested food absorbed into the blood?

A

Water-soluble food molecules like monosaccharides, amino acids, minerals and water-soluble vitamins (eg: vitamin C), can be absorbed into the capillaries by diffusion and active transport.
As the absorption of digested food into the blood increases the water potential of the content in the small intestine, water is drawn into the blood by osmosis. In other words, absorption of digested food in the small intestine is accompanied by absorption of water at the same time. Over 90% of water in food is absorbed in the small intestine.

50
Q

How is digested food absorbed into the lymph?

A

Fatty acids and glycerol enter the epithelium of the villiv by diffusion. In the epithelial cells. they recombine into fine lipid droplets, which then enter the lymph in the lacteals of the lymphatic system. Lipid-soluble vitamins
(eg. vitamins A and D) are also absorbed into the lacteals.
The lipids and lipid-soluble vitamins in the lacteals are transported to the main lymph vessels, and eventually to the. bloodstream near the neck region. They are then carried to all parts of the body through blood vessels.

51
Q

Is there any absorption taking place in the large intestine?

A

Yes: Much of the remaining water is absorbed through the wall of the colon into the blood. Some minerals and vitamins are also absorbed, but very slowly.

52
Q

What is assimilation?

A

Assimilation is the uptake and use of absorbed food molecules by cells foe metabolism.

53
Q

How are water-soluble food molecules transported to other parts of the body?

A

In the small intestine, water-soluble food molecules such as monosaccharides, amino acids, minerals and water-soluble vitamins, are absorbed into the capillaries of the villi. Blood in the capillaries eventually flows to the hepatic portal vein, which carries blood to the liver. In the liver, some food molecules are stored. Some are processed and then carried through the hepatic vein and the vena cava to the heart.
When the heart pumps blood, the absorbed food molecules are transported to all parts of the body through the aorta.

54
Q

How are lipid-soluble food molecule transported to other parts of the body?

A

The lipids and lipid-soluble vitamins absorbed are carried by the lymph in lymph vessels. The lymph vessels eventually join the vein near the neck region. The absorbed lipids and lipid-soluble vitamins are then passed into the blood circulation and enter the heart.
When the heart pumps blood, the absorbed food molecules are transported to all parts of the body through the aorta.

55
Q

What are the fates of absorbed glucose?

A

Glucose is used by body cells for releasing energy by respiration. Excess glucose is converted to glycogen or lipids in the liver. Glycogen is stored in the liver and muscles. Lipids are stored under the skin or around the internal organs.

56
Q

What are the fates of absorbed amino acids?

A

Amino acids are used by cells to make different types of proteins fro growth and repair. They are also the raw materials for making enzymes, antibodies, and some hormones.
Excess amino acids cannot be stored in our body. They are deaminated in the liver.

57
Q

What are the fates of absorbed lipids?

A

Lipids are used by cells to make cell membranes and some hormones.
Lipids are energy reserves in our body. They act as a source of energy for cellular activities when the body is short of glycogen.
Excess lipids may be deposited around the internal organs for protection, or build up in adipose tissue under the skin to reduce heat loss.

58
Q

What are the roles and functions of the liver?

A
  1. Regulation of blood glucose level: After a meal, the blood glucose level rises. The liver converts the excess glucose to glycogen, which is stored in the liver. Between meals, when the blood glucose level falls below a certain level, the liver connects the stored glycogen back to glucose and releases it into the blood.
  2. Storage of glycogen, iron, and lipid-soluble vitamins: The liver breaks down old red blood cells and stores the iron released from the process. The iron is used for making new red blood cells.
  3. Production of bile and vitamin A: Carotene is converted in vitamin A in the liver.
  4. Deamination: Excess amino acids are broken down in the liver through deamination. The amino groups are converted to urea, while the remaining parts are converted to carbohydrates or lipids.
  5. Detoxification: Liver cells contain enzymes which help break down certain mild toxic substances (eg. alcohol and drugs) in the blood to harmless substances in detoxification. The harmless substances are then passed out of the body.
59
Q

What are the features of faeces?

A

Faeces are formed from the undigested and unabsorbed materials in the large intestine. They are semi-solid wastes containing dietary fibre, bacteria, secretions from the alimentary canal, dead cells from the intestinal wall and a small amount of water. They are brown in colour because of the presence of bile pigments. They are temporarily stored in the rectum.

60
Q

How are faeces expelled from the body?

A

At the anus, there is a ring of muscles called the anal sphincter. When the sphincter relaxes and the muscles of the rectum contract, faeces are pushed out through the anus. This process of expelling faeces is called egestion or defaecation.

61
Q

List three beneficial actions of bacteria in our intestines.

A
  1. They produce vitamins B and K, which are absorbed into the blood through the wall of the colon. (Vitamin K is a lipid-soluble vitamin involved in blood clotting and bone metabolism.)
  2. They protect the intestines from infection by disease-causing microorganisms.
  3. They stimulate the development and the activity of the tissues in the immune system.