Guest lecture HPP

Question 1

Premature tooth loss with the root intact prior to what age is a hallmark symptom of HPP?

Answer 1

Five

Question 2

T/F Premature tooth loss without trauma at any age is a hallmark symptom of HPP

Answer 2

True

Question 3

Tooth loss from HPP can happen at any age but what percent will lose a tooth before age 5?

Answer 3

-99%

Question 4

What do you see in a radiograph in HPP in young patients?

Answer 4

Enlarged pulp chambers and abnormal crowns

Question 5

Differential diagnosis of a child with early tooth loss?

Answer 5

• Trauma
• Hypphosphatasia
• Early aggressive periodontal disease

Question 6

What causes HPP?

Answer 6

-Mutations in the ALPL gene

Question 7

What serum test do you see with HPP

Answer 7

-Decreased levels of alkaline phosphotase