Abdo

Question 1

Cuases of a splenomegaly?

Answer 1

Big:
Myeloproliferative disorders - CML
Lymphoproliferative disorders - CLL/lymphoma
Infective other parts of world - malaria/visceral leishmaniasis
infiltrative - amyloidosis

Small:
Portal HTN - cirhosis, thrombosis, 
haemolysis
infections - EBV, infective endocard.
inflammatory - RA, SLE, sjorgrens
rare - sarcoid, amyloid, feltys (RA)

Question 2

leucoerythroblastic?

Answer 2

immature myeloid cells in the periphery?

often with teardrop poikilocytes - myelofibrosis

Question 3

Cuases of hepatomegaly?

Answer 3

Hepatitis - alcohol, viruses, NAFLD, autoimmmune
CLD
CCF - congestion

Other - MACHO
Malignancy - mets
Anatomical - hyperexpansion of the lungs
Congestion - TR, bud chiari
Haematological - Leukaemia/lymphoma
Other - sarcoid/amyloid

inherited - HH, wilsons, a1at