3/17

Question 1

wet macular degeneration

Answer 1

rapid loss of vision due to bleeding secondary to choroidal neovascularization

Question 2

wet macular degeneration treatment

Answer 2

anti VEGF (ranibizumab)

Question 3

lateral geniculate body

Answer 3

part of the infamous visual signal tract

Question 4

bipolar disorder vs schizoaffective disorder

Answer 4

• bipolar is separate incidences of mania and depression

- schizoaffective can have both at the same time

Question 5

akathisia

Answer 5

inability to sit still

Question 6

cholesteatoma

Answer 6

squamous cell debris in a round pearly mass behind tympanic membrane
- from chronic negative pressure with retraction pockets

Question 7

cells increased in COPD

Answer 7

macrophages, neutrophils and CD8 cells

Question 8

systemic mastocytosis

Answer 8

• KIT (tyrosine kinase mutation)

- excessive histamine and tryptase

Question 9

dyenin and kinesin

Answer 9

dynein is retrograde, kinesin is anterograde

Question 10

chrons disease mutation

Answer 10

NOD2 (intracellular microbial receptor), decrease in NF-kB activity and reduced cytokine production

Question 11

raloxifene effects

Answer 11

agonist in bone and antagonist in breast

Question 12

ApoE

Answer 12

mediates remnant uptake

Question 13

ApoA-1

Answer 13

activates LCAT

Question 14

ApoCII

Answer 14

LPL cofactor that catalyzes cleavage

Question 15

ApoB48

Answer 15

chylomicron secretion into lymphatics

Question 16

ApoB100

Answer 16

binds LDL receptors

Question 17

isoniazid and heme synthesis

Answer 17

blocks B6 leading to decrease in ALAS