Classic Labs/Findings II Flashcards

1
Q

Electrical alternans (alternating amplitude on EKG)

A

Pericardial tamponade

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2
Q

Enlarged cells with intranuclear inclusion bodies

A

“Owl eye” appearance of CMV

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3
Q

Enlarged thyroid cells with ground-glass nuclei with central clearing

A

“Orphan Annie” eyes nuclei (papillary carcinoma of the thyroid)

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4
Q

Eosinophilic cytoplasmic inclusion in liver cell

A

Mallory body (alcoholic liver disease)

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5
Q

Eosinophilic cytoplasmic inclusion in nerve cell

A

Lewy body (Parkinson disease)

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6
Q

Eosinophilic globule in liver

A

Councilman body (viral hepatitis, yellow fever), represents hepatocyte undergoing apoptosis

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7
Q

Extracellular amyloid deposition in gray matter of brain

A

Senile plaques (Alzheimer disease)

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8
Q

Giant B cells with bilobed nuclei with prominent inclusions (“owl’s eye”)

A

Reed Sternberg Cells (Hodgkin’s lymphoma)

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9
Q

Glomerulus like structure surrounding vessel in germ cells

A

Schiller Duval bodies (yolk sac tumor)

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10
Q

Hair on end (Crew-cut) appearance on x-ray

A

ß-thalassemia, sickle cell disease (marrow expansion)

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11
Q

hCG elevated

A

Choriocarcinoma, hydatiform mole (occurs with and without embry, and multiple pregnancy)

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12
Q

Heterophile antibodies

A

Infectious mononucleosis (EBV)

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13
Q

Heart nodules (granulomatous)

A

Aschoff bodies (rheumatic fever)

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14
Q

Hexagonal, double-pointed, needle-like crystals in bronchial secretions

A

Bronchial asthma (Charcot-Leyden crystals: eosinophilic granules)

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15
Q

High-level of D-dimers

A

DVT, PE, DIC

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16
Q

Hilar lymphadenopathy, peripheral granulomatous lesion in middle or lower lung lobes (can calcify)

A

Ghon complex (1° TB: Mycobacterium bacilli)

17
Q

“Honeycomb lung” on x-ray or CT

A

Interstitial pulmonary fibrosis

18
Q

Hypercoagulability (leading to migrating DVT’s and vasculitis)

A

Trousseau syndrome (adenocarcinoma of pancreas or lung)

19
Q

Hypersegmented neutrophils

A

Megaloblastic anemia (B12 deficiency: neurlogic symptoms; folate deficiency: no neurological symptoms)

20
Q

Hypertension, hypokalemia, metabolic alkalosis

A

Conn syndrome (primary hyperaldosteronism)

21
Q

Hypochromic, microcytic anemia

A

Iron deficiency anemia, lead poisoning, thalassemia (fetal hemoglobin sometimes present)

22
Q

Increased AFP in amniotic fluid/maternal serum

A

Dating error, anencephaly, spina bifida (neural tube defects)

23
Q

Increased uric acid levels

A

Gout, Lesch-Nyhan syndrome, tumor lysis syndrome, loop and thiazide diuretics

24
Q

Intranuclear eosinophilic droplet-like bodies

A

Cowdry type A bodies (HSV or VZV)

25
Q

Iron-containing nodules in alveolar septum

A

Ferruginous bodies (asbestosis: increased chance of mesothelioma)

26
Q

Keratin pearls on skin biopsy

A

Squamous cell carcinoma

27
Q

Large granules in phagocytes, immunodeficiency

A

Chediak-Higashi disease (congenital failure of phagolysosome formation)

28
Q

“Lead pipe” appearance of colon on abdominal imaging

A

Ulcerative colitis (loss of haustra)

29
Q

Linear appearance of IgG deposition on glomerular and alveolar basement membranes

A

Goodpasture syndrome