DNA And RNA Flashcards

1
Q

DNA

A

Chemical that determines inherited characteristics and contains vast amounts of information in the form of the genetic code

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2
Q

RNA

A

Help convert genetic code of DNA into functional protein

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3
Q

DNA nucleotide

A

Phosphate group backbone
Pentose (deoxyribose)
Nitrogenous base
(Adenine, Guanine, Cytosine, Thymine)

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4
Q

RNA nucleotide

A

Phosphate group backbone
Pentose (ribose)
Nitrogenous base
(Adenine, Guanine, Cytosine, Uracil)

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5
Q

What reaction joins nucleotides?

A

Condensation

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6
Q

What bond is formed between nucleotides?

A

Phosphodiester bonds

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7
Q

What bonds keep 2 nucleotide chains together?

A

Hydrogen bonds

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8
Q

Structure of DNA

A

Double helix, 2 strands of polynucleotides, run anti parallel to each other, twisted into coil

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9
Q

Bonds in adenine, thymine

A

2 hydrogen bonds

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10
Q

Bonds in cytosine, guanine molecules

A

3 hydrogen bonds

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11
Q

What type of molecule is a thymine, cytosine molecule?

A

Pyramidine molecule (ring)

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12
Q

What type of molecule is adenine and guanine molecule?

A

Purine molecules (double rings)

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13
Q

Stability of DNA

A

Stable, phosphodiester bonds are strong covalent bonds

Hydrogen bonds are strong when there are many

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14
Q

Adaptations of DNA

A

Stable, passes onto next gen without change
2 strands joined with hydrogen bonds, allow them to be easily separated during DNA replication and protein synthesis
Base pairs in helical cylinder, genetic info protected from outside chemical and physical force

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15
Q

Discovery of DNA

A

Watson and Crick, Cavendish lab in Uni of Cambridge
Completed with Franklin, Pauling,Wilkins
X-rays produced images of DNA
Chargaff’s rule, DNA should have 1:1 ratio of pyramidine, purine bases
Watson led genome project

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16
Q

Comparison between eukaryotic and prokaryotic chromosomes

A

DNA, v long, linear, associated with histones
DNA, short, circular, not associated with proteins
Histones allow more folding

17
Q

DNA and chromosomes

A

Nucleosome, 8 histones with DNA wrapped around twice

Chromosome=DNA molecule and histones

18
Q

Mitochondrial and chloroplast DNA

A

Mitochondrial DNA, similar to prokaryotic DNA
Chloroplasts DNA, similar to prokaryotic DNA
Not associated with proteins

19
Q

Genes

A

Base seq of DNA, codes for amino acid seq of polypeptide

20
Q

Locus

A

Gene occupies fixed position on chromosome

21
Q

Triplet code

A

Seq of 3 base code for 1 amino acid

22
Q

Exons

A

Code for animo acid seq

23
Q

Introns

A

Separate exons by non coding regions

24
Q

mRNA

A

Bases complementary to 1 of the DNA strands
Formed in nucleus, moves to ribosomes
Acts as a template upon which proteins are made
Easily broken down, only exists when needed, less wasteful

25
Q

tRNA

A
80 nucleotides long
Clover leaf structure
Shape held together by hydrogen bonds
2 distinctive ends
1 end, amino acid attachment site, other site, anticodon, complementary to mRNA codon
Chemically more stable than mRNA
Only produced when necessary
26
Q

Universal

A

Same codon codes for same amino acid in all organisms

27
Q

Non overlapping

A

Each base sequence is only read once

28
Q

Degenerate

A

Most amino acids have more than 1 codon