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SBMS2106 > 07 - Neuropharmacology > Flashcards

07 - Neuropharmacology Flashcards

1
Q

chlorpromazine

A

typical antipsychotic

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2
Q

clozapine

A

atypical antipsychotic

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3
Q

bromocriptine

A

D2 agonist

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4
Q

ropinirole

A

D2 agonist

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5
Q

apomorphine

A

D2 agonist

rescue treatment for off effects

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6
Q

L-DOPA

A

DA precursor

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7
Q

carbidopa

A

peripheral DDC inhibitor

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8
Q

benserazide

A

peripheral DDC inhibitor

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9
Q

salegiline

A

MAO-B inhibitor

giline

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10
Q

rasagiline

A

MAO-B inhibitor

giline

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11
Q

tolcapone

A

COMT inhibitor

capone

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12
Q

entacapone

A

COMT inhibitor

capone

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13
Q

amantadine

A

Stimulants of DA release

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14
Q

benzatropine

A

anti-muscarinic

tropine

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15
Q

moclobemide

A

MAO inhibitor
reversible inhibitor for MAO-A,
which metabolizes NE, E and 5-HT

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16
Q

amitriptyline

A

TCA

non-selective inhibitors of NET and SERT

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17
Q

imipramine

A

TCA

non-selective inhibitors of NET and SERT

18
Q

fluoxetine (Prozac)

A

SSRI
(xetine)
selective inhibitor of SERT

19
Q

citalopram

A

SSRI

selective inhibitor of SERT

20
Q

paroxetine

A

SSRI
(xetine)
selective inhibitor of SERT

21
Q

sertraline

A

SSRI

selective inhibitor of SERT (sert)

22
Q

bupropion

A

NRI

selective inhibitor of NET

23
Q

venlafaxine

A

SNRI

inhibitors of SERT and NEI

24
Q

mianserin

A

atypical anti-depressants
monoamine receptor antagonists
alpha(2) heteroreceptor blocker

25
Q

trazodone

A

atypical anti-depressants

post-synaptic 5-HT(2A) blocker

26
Q

diazepam

A 
BDZ
potentiates GABA(A) receptor on GABAergic neurone
27
Q

lorazepam

A 
BDZ
potentiates GABA(A) receptor on GABAergic neurone
28
Q

midalozam

A 
BDZ
potentiates GABA(A) receptor on GABAergic neurone
29
Q

flumazenil

A

BDZ antagonist

30
Q

zolpidem

A

Z drug

31
Q

phenobarbital

A

enhances GABA(A) receptors

32
Q

vigabatrin

A

inhibits GABA transaminase

33
Q

valproate

A

1) inhibits GABA transaminase

2) inhibits VG Na+ channels

34
Q

carbamazepine

A

inhibits VG Na+ channels

35
Q

phenytoin

A

inhibits VG Na+ channels

36
Q

ethosuximide

A

inhibits T-type Ca2+ channels

37
Q

gabapentin

A

novel anti-epileptic

38
Q

pregabalin

A

novel anti-epileptic

39
Q

lamotrigine

A

1) inhibits VG Na+ channels
2) inhibits T-type Ca2+ channels
3) inhibits glutamate release

40
Q

opioids

A

activates mule receptors on GABAergic neurone

41
Q

THC

A 
cannibinoids
activates CB1 (cannabinoid 1) receptor on GABAergic neurone terminal

SBMS2106 (4 decks)

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