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Pathophysiology 1 MCQ > Liver > Flashcards

Liver Flashcards

1
Q 
Which infection cannot be prevented by vaccination?
 HAV
 HBV
 HCV
 HDV
 HEV
A

HCV

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2
Q 
In which viral hepatitis is pregnancy a risk factor for a fulminant course?
 HAV
 HBV
 HCV
 HDV
 HEV
A

HEV

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3
Q 
Laënnec cirrhosis is caused by:
 alcohol
 biliary obstruction
 congestive heart failure
 drug effect
 Wilson’s disease
A

alcohol

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4
Q 
Cirrhosis may cause the following except:
 spontaneus bacterial peritonitis
 bleeding tendency
 hepatorenal syndrome
 iron deficiency
 hepatocellular carcinoma
A

spontaneus bacterial peritonitis

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5
Q 
“Caput medusae” is the name:
 of the dying jellyfish
 when someone dies from the sting of a jellyfish
 for dilated capillaries
 for dilated periumbilical veins
 for spider nevi
A

for dilated periumbilical veins

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6
Q 
Symptoms of hepatic encephalopathy, except:
 reversal of sleep/wake cycle
 foetor hepatis
 asterixis
 vomiting
 paralysis
A

paralysis

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7
Q 
Foetor hepatis is the name of:
 the fetal liver
 alcoholic steatosis
 alcoholic cirrhosis
 alcoholic steatohepatitis
 the characteristic smell of the breath of cirrhotic patients
A

the characteristic smell of the breath of cirrhotic patients

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8
Q 
The most common cause of severe acute parenchymal liver lesion:
 paracetamol overdose
 mushroom poisoning
 acute alcohol intoxication
 cocain overdose
 viral hepatitis
A

paracetamol overdose
mushroom poisoning

cocain overdose

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9
Q

What is the idiosyncratic reaction?
drug poisoining of mentally retarded people
when two different drugs have the same adverse effect
severe adverse effect of a drug administered at the usual dose
severe adverse effect resulting from the interaction of two drugs
severe adverse effect resulting from the interaction of more than two drugs

A

severe adverse effect of a drug administered at the usual dose

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10
Q 
What is the likelihood that an HBV infection becomes chronic in a newborn?
0%
 1–10%
 10–20%
 40–50%
90%
A

1–10%

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11
Q

Asterixis is a symptom occurring in hepatic encaphalopathy. What is it?
reading cartoons obsessively
visual disturbance: seeing star-like lights
momentarily losing the ability to hyperextend the wrist joint
the name of convulsions seen in this state
reversal of the sleep/wake pattern

A

momentarily losing the ability to hyperextend the wrist joint

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12
Q

What is hepatorenal syndrome?
severe lesion of the kidney parenchyma seen in liver disease
severe lesion of the liver parenchyma seen in kidney disease
any condition in which there is simultaneous liver and kidney dysfunction
severe impairment of renal function seen in liver disease
severe impairment of liver function seen in kidney disease

A

severe impairment of renal function seen in liver disease

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13
Q 
What percentage of deaths occuring under 70 years of age in Hungary are related to alcohol consumption?
5%
10%
15%
20%
25%
A

20%

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14
Q 
The increase of which enzyme activity indicates the lesion of liver parenchyma?
 LDH
 ALAT
 ALP
 GGT
 CPK
A

ALAT

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15
Q 
Liver disease may cause
hyperglycemia
hypoglycemia
bleeding tendency
fatty liver
A

hyperglycemia
(?hypoglycemia?)
bleeding tendency
fatty liver

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16
Q 
Clinical signs of liver disease include:
koilonychia
palmar erythema
hypertrichosis
spider nevi
A

spider nevi

17
Q 
The tolerance for barbiturates in alcoholics is:
increased in the sober state
increased in the drunken state
decreased in the drunken state
decreased in the sober state
A

increased in the sober state

decreased in the drunken state

18
Q 
Chronic hepatitis is never caused by:
HDV
HCV
HBV
HAV
A

HAV

19
Q

It is true about HCV infection:
fulminant course is common
it is the most likely to turn into chronic hepatitis
there is no effective antiviral drug against it
there is no effective vaccine against it

A

it is the most likely to turn into chronic hepatitis
(?there is no effective antiviral drug against it? it came out really recently and is expensive as fuuuck (i think 81.000 USD/month) so idk if it counts here)
there is no effective vaccine against it

20
Q 
Consequences of cirrhosis in the liver:
fewer microvilli on the liver cells
more collagen production
capillarization of sinusoids
loss of parenchyma
A

fewer microvilli on the liver cells

capillarization of sinusoids
loss of parenchyma

21
Q 
Which materials are primarily excreted in the liver?
cholesterol
bilirubin
copper
iron
A

cholesterol

bilirubin

22
Q 
Which materials are stored in the liver?
nutrients
iron
Vitamins
ketone bodies
A

nutrients
iron
Vitamins (in lecture I found one slide mentioning all three, and one slide mentioning just nutrients, and iron, so I guess all three is correct)

23
Q 
Which materials coming through the portal vein are filtered and stored in the liver?
glucose
fatty acids and monoglycerides
amino acids
ketone bodies
A

glucose

fatty acids and monoglycerides

24
Q 
Which clinical states are associated with a higher risk for hepatocellular carcinoma?
chronic HBV infection
NASH
cirrhosis
NAFLD
A

chronic HBV infection
NASH
cirrhosis
NAFLD

25
Q 
Both portal hypertension and decreased parenchyma contribute in cirrhotic patients to the development of:
ascites
prolonged protrombin time
hepatic encephalopathy
splenomegaly
A

ascites
prolonged protrombin time
hepatic encephalopathy

26
Q

The ammonia level of plasma is decreased by the:
descreased activity of glutamine synthetase in the muscle
increased activity of glutamine synthetase in the liver
increase of renal perfusion
increased activity of urea cycle

A

increased activity of glutamine synthetase in the liver
increase of renal perfusion
increased activity of urea cycle

27
Q 
Which hereditary condition may cause progressive parenchymal lesion in the liver?
hemophilia
Wilson’s disease
Gilbert’s syndrome
hemochromatosis
A

Wilson’s disease

hemochromatosis

28
Q

The consequence of an increased NADH/NAD ratio in the liver of alcoholic patients:
gluconeogenesis is inhibited
citrate cycle is inhibited
beta-oxidation of fatty acids is inhibited
MEOS is induced

A

gluconeogenesis is inhibited
citrate cycle is inhibited
beta-oxidation of fatty acids is inhibited

29
Q

In patients with liver failure who have high level of ammonia in the plasma:
the activity of glutamine synthetase is increased in the muscle
the activity of glutamine synthetase is increased in the liver
the amount of glutamine is increased in the astrocytes
the amount of glutamate is increased in the synapses of the brain

A

?

Pathophysiology 1 MCQ (16 decks)

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