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Pathophysiology 1 MCQ > GI Diseases > Flashcards

GI Diseases Flashcards

1
Q

Which drug is not used in H pylori eradication protocols?
clarithromycin+amoxicillin (combined antibiotics treatment)
metronidazole (antibiotic covering the anaerobic bacteria)
NSAIDs
Bismuth
Proton pump inhibitor

A

NSAIDs

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2
Q 
Pathogenic factors of H pylori:
 Cytotoxin associated gene a (Caga)
 Inflammation
 Hyperacidity
 Endotoxin (LPS)
A

Cytotoxin associated gene a (Caga)
Inflammation
Hyperacidity
Endotoxin (LPS)

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3
Q 
Which one plays a role in H pylori toxin production?
 Cytotoxin associated gene A (CagA)
 NOD-CARD mutation
 Hyperacidity
 gastroesophageal reflux
 gastrin hypersecretion
A

Cytotoxin associated gene A (CagA)

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4
Q

Which statements are false about Crohn’s disease?
it may cause damage to any part of the gastrointestinal tract
a fistula may develop
it often affects the terminal ileum
It starts in the rectum and proceeds proximally
It has extraintestinal manifestations

A

It starts in the rectum and proceeds proximally

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5
Q 
Which of the following plays a role in gastric acid production?
 enterochromaffin-like (ECL) cells
 acetylcholine
 prostacyclin
 somatostatin
A

enterochromaffin-like (ECL) cells

acetylcholine

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6
Q 
Which of the following plays a role in the regulation of gastric acid production?
 acetylcholine
 gastrin
 histamine
 tromboxane
A

gastrin

histamine

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7
Q 
What are the potential symptoms of colon cancer?
 bloody stools
 alternating diarrhea and constipation
 anemia
 jaundice
A

bloody stools
alternating diarrhea and constipation
anemia

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8
Q 
Which are the symptoms of hyperacidity:
 Heartburn
 Chest pain
 Nausea
 Pain relief after eating
A

Heartburn
Chest pain
?Nausea
?Pain relief after eating

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9
Q 
Which of the following are symptoms of hyperacidity:
 intense abdominal pain after eating
 pain relief following eating
 nausea, vomiting
 heartburn
A

heartburn

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10
Q 
Which ones are NOT potential complications of GERD:
 Gastric ulcer
 Weight loss
 Esophagus varicies
 Eosphageal stirctures
A

Gastric ulcer

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11
Q 
Which ones are NOT potential complications of GERD:
     Weight loss
 Esophagus varicies
 Achalasia
 Gastric ulcer
A

Gastric ulcer

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12
Q 
What are the potential complications of reflux disease?
 weight loss
 esophageal strictures
 Achalasia
 peptic ulcer
A

weight loss
esophageal strictures
?Achalasia

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13
Q 
Which diseases are linked to H pylori infection?
 Gastric ulcer
 Duodenal ulcer
 Gastric cancer
 Mucosa associated (MALT) lymphoma
A

Gastric ulcer
?Duodenal ulcer
Gastric cancer
Mucosa associated (MALT) lymphoma

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14
Q 
Which drug classes are used to block the hyperacidity?
 Prostaglandin analogs
 Histamine H2 antagonists
 Gastrin
 Proton pump inhibitors
A

Histamine H2 antagonists

Proton pump inhibitors

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15
Q 
Which drug classes can reduce the hyperacidity?
 Antacids
 NSAIDs
 Histamine H2 receptor antagonists
 Gastrin
A

Antacids

Histamine H2 receptor antagonists

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16
Q 
Which ones are the potential complications of gastroesophageal reflux?
 Barrett metaplasia
 Esophageal cancer
 nutcracker esophagus
 duodenal ulcer
A

Barrett metaplasia

Esophageal cancer

17
Q

Which ones are the potential complications of gastroesophageal reflux?
Barrett metaplasia
Barrett’s esophageal ulcer achalasia
esophageal cancer

A

Barrett metaplasia
Barrett’s esophageal ulcer

esophageal cancer

18
Q 
Which methods are not used in colorectal cancer screening?
 ERCP
 Hemoccult test
 esophagogastroduodenoscopy (EGD)
 Colonoscopy
A

ERCP

esophagogastroduodenoscopy (EGD)

19
Q 
Which method is not used in colorectal cancer screening?
 Tumor marker tests
 Hemoccult
 colonoscopy
 ERCP
A

Tumor marker tests *( my teaches said it was only to see progression of the disease, but I am not sure what the other professors would say)

ERCP

20
Q 
Which methods can be used for colorectal cancer screening?
 Tumor marker tests
 Heamoccult test
 colonoscopy
 ERCP
A

?Tumor marker tests
Heamoccult test
colonoscopy

21
Q

What can cause colorectal cancer in young adults (<40 years)?
hereditary nonpolyposis colorectal cancer (HNPCC) linked mutations
Lynch syndrome
familial adenomatous polyposis
somatic mutations of the APC gene

A

?HNPCC linked mutations
Lynch syndrome
?familial adenomatous polyposis

22
Q 
What features or stages may occur in Crohn's disease?
it might  be asymptomatic in remission
 fibrostenotic form
 fistulizing Crohn's disease
 Reflux- type disease
A

it might be asymptomatic in remission

fistulizing Crohn’s disease

23
Q

What stages may occur in Crohn’s disease?
dismotility
the inflammation may penetrate deep into the tissues of the intestines
Reflux- type disease
muscular hypertrophy may occur in the intestines

A

the inflammation may penetrate deep into the tissues of the intestines

muscular hypertrophy may occur in the intestines

24
Q 
Which of the following plays a role in the development of Crohn's Disease?
 Inflammation
autoantibodies
 intestinal immune system
 gut flora (microbiota)
A 
Inflammation
autoantibodies
 intestinal immune system
 gut flora (microbiota)
25
Q 
Which of the following plays a role in the development of Crohn's Disease?
 gut flora (microbiota)
 hereditary factors
 intestinal immune system
 reduced gastric acidity
A 
gut flora (microbiota)
 hereditary factors
 intestinal immune system
26
Q 
What is used in the treatment of IBD?
 Biological drugs (anti-TNF ab)
 immune suppression
 surgical resection
 antacids
A

Biological drugs (anti-TNF ab)
immune suppression
surgical resection

27
Q 
Which ones are used in the treatment of IBD?
 glucocorticoid steroids
 proton pump inhibitors
Biological drugs (anti-TNF ab)
 NSAIDs
A

Biological drugs (anti-TNF ab)

28
Q

Which ones are commonly seen in ulcerative colitis?
inflammation of the mucosa, predominantly localized to the colon
superficial damage occurs to the mucosa layer
diarrhea, colic
anemia

A

inflammation of the mucosa, predominantly localized to the colon
superficial damage occurs to the mucosa layer
diarrhea, colic
anemia

29
Q

Which statements are true about ulcertive colitis (UC)?
Colonoscopy and biopsy are necessary for the diagnosis
It may be treted with antacids
an autimmune mechanism is involved in the pathogenesis of UC
Smoking may provoke a relapse

A

Colonoscopy and biopsy are necessary for the diagnosis

an autimmune mechanism is involved in the pathogenesis of UC

30
Q

Which statements are true about ulcertive colitis (UC)?
The sigmoid colon and the rectum are affected in most cases
Colonoscopy is needed for the diagnosis
Biopsy is needed for the diagnosis
An autimmune mechanism is involved in the pathogenesis of UC

A

The sigmoid colon and the rectum are affected in most cases
Colonoscopy is needed for the diagnosis
Biopsy is needed for the diagnosis
An autimmune mechanism is involved in the pathogenesis of UC

31
Q 
What are the features of celiac disease?
prevalence of 1%
Chronic diarrhea, abdominal pain
Subfebrility/fever
bloody, mucouos diarrhea
A

prevalence of 1%
Chronic diarrhea, abdominal pain
Subfebrility/fever

32
Q 
What are the features of celiac disease?
constipation
weight loss
type 1 hypersensitivity reaction
it may develop at any age
A

weight loss

it may develop at any age

33
Q 
What are the features of celiac disease?
dermatitis herpetiformis
high tissue transglutanimase (tTG) IgG/IgA antibody titer
Steatorrhea 
intestinal villi flattening
A

dermatitis herpetiformis
high tissue transglutanimase (tTG) IgG/IgA antibody titer
Steatorrhea (can be?!)
intestinal villi flattening

34
Q 
What are the features of celiac disease?
A prevalence of 10% in IgA deficiency
The most sensitive screening test is tTG IgG
Megaloblastic anemia
familial prevalence is low
A

A prevalence of 10% in IgA deficiency

Megaloblastic anemia

35
Q

Which statements are true about irritable bowel syndrome?
Organic diseases must be excluded before making a diagnosis
It accounts for 20% of gastrointestinal symptoms
It causes a complex problem for differential diagnosis
It is an absorption disorder

A

Organic diseases must be excluded before making a diagnosis

It causes a complex problem for differential diagnosis

Pathophysiology 1 MCQ (16 decks)

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