Membrane Phys Flashcards

1
Q

How much of the body is total body water?

A

50-70%

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2
Q

What is the relationship of water and fat?

A

Inversely proportional

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3
Q

What are the two major fluid compartments?

A

ICF and ECF

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4
Q

What separated the ICF and ECF?

A

Cell membrane

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5
Q

What two things make up the ECF?

A

Plasma and Interstitial Fluid

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6
Q

What separates the two components of ECF?

A

Capillary wall

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7
Q

Which of the fluid compartments contains cations of K+ and Mg2+ w/proteins and organic phosphates?

A

ICF

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8
Q

Which of the fluid compartments has cations of Na+ w/ anions of Cl- and HCO3-?

A

ECF

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9
Q

Each compartment must have equal concentrations of anions and cations is what principle?

A

Principle of Macroscopic Electroneutrality

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10
Q

What two things make up the cell membrane?

A

Lipids and proteins

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11
Q

What three things make up the lipid component?

A

Cholesterol, phospholipids, and glycolipids

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12
Q

What items are lipid-soluble?

A

CO2, O2, fatty acids, steroid hormones

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13
Q

What items are water soluble?

A

Ions, glucose, amino acids

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14
Q

What five things make up the protein component of the cell membrane?

A
  1. transporters 2. cell-surface antigens 3. hormone receptors 4. enzymes 5. ion and water channels
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15
Q

What are the two features of phospholipids?

A

Phosphorylated glycerol backbone “head” and two fatty acid tails

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16
Q

What is the relationship of the head of the phospholipid to water?

A

Hydrophilic

17
Q

What is the relationship of the tail of the phospholipid tails?

A

Hydrophobic

18
Q

Due to the hydrophobic properties of the fatty acid tails, what is created to form a cell membrane?

A

Phospholipid bilayer

19
Q

What are the two types of proteins in the cell membrane?

A

Integral and Peripheral

20
Q

What are the characteristics of integral proteins?

A

Embedded and anchored to the CM by hydrophobic interactions

21
Q

What are the characteristics of peripheral proteins?

A

Not embedded in CM or bonded but attached by electrostatic interactions

22
Q

Name two examples of peripheral proteins.

A

Ankyrin, Cl-/HCO3- exchanger

23
Q

What is created when there is a cis double bond in a phospholipid?

A

kink, allows for better saturation and flow