Rate-limiting enzymes Flashcards

1
Q

Glycolysis

A

Phosphofructokinase-1 (PFK-1)

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2
Q

Gluconeogenesis

A

Fructose-1,6-bisphosphatase

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3
Q

TCA cycle

A

Isocitrate dehydrogenase

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4
Q

Glycogen synthesis

A

Glycogen Synthase

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5
Q

Glycogenolysis

A

Glycogen Phosphorylase

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6
Q

Hexose Monophosphate (HMP) shunt

A

Glucose-6-phosphate dehydrogenase (G6PD)

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7
Q

De novo pyrimidine synthesis

A

Carbamoyl phosphate synthetase II

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8
Q

De novo purine synthesis

A

Glutamine-PRPP amidotransferase

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9
Q

Urea cycle

A

Carbamoyl Phosphate Synthetase I

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10
Q

Fatty acid synthesis

A

Acetyl-CoA carboxylase (ACC)

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11
Q

Fatty acid oxidation

A

Carnitine acyltransferase I

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12
Q

Ketogenesis

A

HMG-CoA synthase

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13
Q

Cholesterol synthesis

A

HMG-CoA reductase

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14
Q

Phosphofructokinase-1 (PFK-1)

A

Glycolysis

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15
Q

Fructose-1,6-bisphosphatase

A

Gluconeogenesis

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16
Q

Isocitrate dehydrogenase

A

TCA cycle

17
Q

Glycogen Synthase

A

Glycogen synthesis

18
Q

Glycogen Phosphorylase

A

Glycogenolysis

19
Q

Glucose-6-phosphate dehydrogenase (G6PD)

A

Hexose Monophosphate (HMP) shunt

20
Q

Carbamoyl phosphate synthetase II

A

De novo pyrimidine synthesis

21
Q

Glutamine-PRPP amidotransferase

A

De novo purine synthesis

22
Q

Carbamoyl Phosphate Synthetase I

A

Urea cycle

23
Q

Acetyl-CoA carboxylase (ACC)

A

Fatty acid synthesis

24
Q

Carnitine acyltransferase I

A

Fatty acid oxidation

25
Q

HMG-CoA synthase

A

Ketogenesis

26
Q

HMG-CoA reductase

A

Cholesterol synthesis