Elimination vs Substitution Flashcards
What are 5 substances that are nucleophiles only?
F- Cl- Br- CN- I-
What are 2 substances that are strong bases?
- OH
- OCH2CH3
What are 2 substances that are weak bases and weak nucleophiles?
CH3OH
H2O
What reaction mechanism do reactions with an alkoxide (-OCH2CH3) tend towards?
E2
What mechanism will the reaction of a primary alkyl halide with a strong base such as -OH tend towards?
SN2
What mechanism will the reaction of a secondary alkyl halide with a strong base such as -OH tend towards?
E2
What will the E2 reaction of a secondary alkyl halide with -OH produce?
An alkene
What mechanism will the reaction of a tertiary alkyl halide with a strong base such as -OH tend towards?
E2
What mechanism will the reaction of a primary alkyl halide with a weak base/weak nucleophile tend towards?
SN2 (but very slowly)
What mechanism will the reaction of a secondary alkyl halide with a weak base/weak nucleophile tend towards?
SN1 and E1
What can be said about SN1 and E1 reactions?
They occur together. You tend not to have one without the other
What mechanism will the reaction of a tertiary alkyl halide with a weak base/weak nucleophile tend towards?
SN1 and E1
To form an alkene from an alkyl halide via an elimination reaction, what must it be reacted with?
A base
To form an alkene from an alcohol via an elimination reaction, what must be used as a catalyst?
An acid
What two things is the formation of alkenes from alcohols called?
Elimination
Dehydration
