Module 17- Blood Disorder part 1 Flashcards

1
Q

Blood is composed of 55% ___ and 45% ___

A

plasma fluid

formed elements

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2
Q

The 45% formed elements consists of:
__% RBC
__% WBC/platelets

A

44

1

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3
Q

What does hematocrit mean?

A

Volume percentage of RBC in whole blood

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4
Q

What is the normal range for a hematocrit?

A

37-54%

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5
Q

What is the normal range for a hemoglobin?

A

12-18 g/100ml

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6
Q

The normal level for an INR test is ______?

A

1

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7
Q

The normal range for a bleeding time test is?

A

1-6 min

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8
Q

What are the 3 types of Bleeding Time Tests?

A

Duke
Ivy
Modified Ivy

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9
Q

PT stands for _______ and figures out how long it takes you to _______

A

Prothrombin Time

clot

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10
Q

The normal time for a PT test is?

A

11-15 sec

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11
Q

PTT stands for______ and normal ranges are ____?

A

Partial Thromboplastin Time

68-82 sec

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12
Q

If plasma is allowed to clot it is called?

A

serum

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13
Q

Plasma is composed of 90% ____ and 10% _____

A

water

plasma proteins

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14
Q

RBC’s are called _______

A

erythrocytes/corpuscles

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15
Q

Why are RBC’s called corpuscles?

A

have no nuclei

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16
Q

RBC’s are ______ in shape and contain _____

A

biconcave

hemoglobin

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17
Q

If your hemoglobin range is low you have?

A

anemia

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18
Q

if your hemoglobin range is high you have?

A

pathologic condition

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19
Q

What are the two groups of WBC’s?

A

granulocytes

Agranulocytes

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20
Q

WBC’s are able to pass through walls at _____ and go into the ______

A

capillary ends

connective tissue

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21
Q

What are the 3 WBC granulocytes?

A

neutrophil
eosinophil
basophil

22
Q

What are the 2 WBC agranulocytes?

A

lympocytes

monocytes

23
Q

______ are 1/4 the size of a RBC?

A

Platelets

24
Q

The small lymphocytes are known as _____ and _____ cells

A

T

B

25
Q

What are the 2 main jobs of platelets?

A

blood clot formation

blood clot dissolution

26
Q

Anemia or “____ _____” is a reduction of the _____ concentration?

A

tired blood

hemoglobin concentration

27
Q

Acute blood loss occurs from ______ and causes an anemia?

A

trauma

disease

28
Q

Anemia can be caused by a destruction of RBC’s which would be termed a _______ anemia?

A

Hemolytic

29
Q

What is a common type of hemolytic anemia?

A

sickle cell anemia

30
Q

What is a common type of ACQUIRED hemolytic anemia due to pregnancy complications?

A

Erythroblastosis fetalis

31
Q

What are reasons for diminished production of RBC’s which causes an anemia?

A

nutritional deficiency

bone marrow failure

32
Q

Pernicious anemia is due to?

A

B12 bitamin absorption deficiency

33
Q

Bone Marrow Failure is also termed ______ anemia?

A

Aplastic

34
Q

Aplastic anemia is due to a _____ decrease in ____ cells

A

quantitative

all

35
Q

What is the most prevalent form of anemia?

A

iron deficiency

36
Q

What is the second most prevalent anemia?

A

Anemia of Chronic Disease

37
Q

______ is an inherited blood condition which affects mediterranean, african, middle eastern and southeast asian descents?

A

Thalassemia

38
Q

Thalassemia is an __ or ____ production of hemoglobin

A

absent

decreased

39
Q

What anemia is seen as a low reticulocyte count?

A

Anemia of Chronic Disease

40
Q

What is the treatment for Thalassemia patients?

A

hematopoietic stem-cell transplant

41
Q

Iron deficiency anemia is a _____, ____ anemia?

A

hypochromic

microcytic

42
Q

hypochromic means?

A

low hemoglobin

43
Q

iron deficiency anemia occurs more in what gender/age?

A

young women

44
Q

When hemoglobin levels are at ____ or below the tongue appears smooth and shiny

A

10

45
Q

What are the 2 forms of megaloblastic anemia?

A

pernicious- b12 deficiency

folate anemia- folic acid deficiency

46
Q

What 2 vitamins are necessary in RBC production in the bone marrow?

A

b12

folate

47
Q

Pernicious anemia is due to a deficiency of the ______ factor?

A

intrinsic

48
Q

Intrinsic factor is related to pernicious anemia because it is responsible for?

A

absorption of B12

49
Q

Pernicious anemia affects people over age?

A

40

50
Q

What is the tx for pernicious anemia?

A

B12 shots 2 x wk

51
Q

Folic acid deficiency in pregnant women can cause?

A

Spina Bifida

52
Q

Which Megaloblastic anemia has CNS involvement?

A

Pernicious