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Toxicologia - 2019 > Aflatoxina ​ > Flashcards

Aflatoxina ​ Flashcards

1
Q

Aflatoxina - Origem

A

Aspergillus flavus

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2
Q

Aflatoxina - Alvos 2

A

Alta Especificidade → Ligação Covalente ao DNA

Nível Molecular → DNA e RNA

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3
Q

Aflatoxina - Problema / Consequências 2

A

INTERFERÊNCIA COM O MOLDE DO DNA

Pode gerar neoplasias → hepáticas / renais

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4
Q

Aflatoxina - Mecanismo de Ação 2

A

Biotransformação → formação de eletrólitos

Ligação covalente ao DNA + 2,3 epóxido aducto de guaninaadenina = mutação
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Toxicologia - 2019 (132 decks)

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