Parasite 5

Question 1

what are included in parasites?

Answer 1

single celled protozoa
multicellular worms
ectoparasites

Question 2

what is the innate immune response like to protozoan parasites?

Answer 2

similar to bacteria both intracellularly and extracellularly

Question 3

what is the innate immune response like to metazoan parasites?

Answer 3

IgE bind to parasites, to big to be phagocytosed so eosinophils degranulate on surface of worms like ADCC

Question 4

what is adaptive immunity like toward protozoan parasites?

what what type of response toward intracellular protozoa?

Answer 4

intracellularly- similar to intracellular bacteria and fungi, CTLs and CD4+ T helper cells play

Th1 response

extracellularly - Th1/Th17 response like other extracellular pathogens

antibodies against parasites similar to extra/intracellular bacteria/fungi

prevents binding of pathogens

neutralization

ADCC

Question 5

what is adaptive immunity like towards metazoan parasites?

Answer 5

also multicellular, these are extracellular so mainly a Th2 (IL5) response and humoral response resulting IgE antibodies and eosinophil activation

Question 6

what is the effect of Th2 response towards metazoan parasites or helminths?

Answer 6

eosinophil activation

helminth death

Question 7

how does the immune system respond to helminth invasion?

Answer 7

antibody production leading to mast cell degranulation

intestinal mucus secretion and peristalsis

eosinophil activation

macrophage activation