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Pathophysiology - Final Exam > Renal - PowerPoint/1 > Flashcards

Renal - PowerPoint/1 Flashcards

1
Q

nephrotic or nephritic syndrome - HTN

A

nephritic

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2
Q

inflammation of the glomerulus

A

flomerulonephritis

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3
Q

glomerulonephritis blood tests results reveal elevated what

6

A
  1. serum urea
  2. creatinine
  3. anti-DNase B
  4. strept Abs
  5. antistreptolysin
  6. antistreptokinase
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4
Q

increased renin secretion and decreased GFR leads to

A

increased BP

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5
Q

nephrotic or nephritic syndrome - azotemia

A

nephritic

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6
Q

glomerulonephritis leads to elevated BP that is caused by

2

A

increased renin secretion and decreased GFR

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7
Q

nephrotic or nephritic syndrome - hyperlipidemia and lipiduria

A

nephrotic

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8
Q

glomerulonephritis - urine becomes

2

A

dark

cloudy

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9
Q

oliguria, HTN, and edema are sx of

A

glomerulonephritis

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10
Q

hyperlipidemia and lipiduria

A

nephrotic syndrome

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11
Q

oliguria, HTN, and variable proteinuria is to

A

nephritic syndrome

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12
Q

glomerulonephritis mechanism of injury - deposition of circulating what?

A

soluble Ag-Ab complexes, often with complement fragments (type III hypersensitivity)

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13
Q

nephrotic syndrome protein excretion is caused by

A

glomerular injury

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14
Q

nephritic syndrome proteinuria value

A

< 3g/day

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15
Q

glmerulonephritis can be caused by

5

A
  1. immunology
  2. drugs/toxins
  3. vascular disorders
  4. systemic disease (secondary)
  5. viral
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16
Q

vit D def is to

A

nephrotic syndrome

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17
Q

nephrotic or nephritic syndrome - oliguria

A

nephritic

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18
Q

glomerulonephritis drug tx

2

A
  1. glucocorticoids for inflammation

2. antihypertensives

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19
Q

hypoalbuminemia with edema

A

nephrotic syndrome

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20
Q

nephritic syndrome sx

5

A
  1. hematuria
  2. azotemia
  3. oliguria
  4. HTN
  5. variable proteinuria
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21
Q

glomerulonephritis mechanisms of injury include

3

A
  1. deposition of Ag-Ab complexes into basement membrane
  2. Abs acting against Ags planted in the glomerulus
  3. non immune factors i.e. drugs, toxins, ischemia
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22
Q

elevated serum urea and creatinine levels are signature for

A

glomerulonephritis

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23
Q

nephrotic or nephritic syndrome - proteinuria > 3.5g/day

A

nephrotic

24
Q

glomerulonephritis two major symptoms if severe are

A
  1. hematuria w/ RBC casts

2. proteinuria >3.5 g/day w/ albumin as the major protein

25
Q

excretion of > 3.5 g of protein in the urine per day

A

nephrotic syndrome

26
Q

glomerulonephritis mechanism of injury - Abs reacting …

A

in situ against planted Ags within the glomerulus (type II hypersensitivity - cytotoxic)

27
Q

nephrotic syndrome

A

excretion of > 3.5 g of protein in the urine per day

28
Q

nephrotic syndrome proteinuria level

A

> 3.5g/day

29
Q

glomerulonephritis causes pain where

2

A

flank

back

30
Q

glomerulonephritis edema happen where initially?

2

A

initially, facial and periorbital edema - then general edema follows

31
Q

glomerulonephritis tx

3

A
  1. sodium restriction
  2. protein and fluid intake decreased
  3. drugs
32
Q

glomerulonephritis

A

inflammation of the glomerulus

33
Q

hematuria with RBC casts is to

A

severe glomerulonephritis symptom

34
Q

nephrotic or nephritic syndrome - hypoalbuminemia < 3.5

A

nephrotic

35
Q

proteinuria > 3-5g/day with albumin (macroalbuminuria) as the major protein in urine is to

A

severe glomerulonephritis symptom

36
Q

nephrotic or nephritic syndrome - edema

A

nephrotic

37
Q

most common infection that leads to glomerulonephritis

A

strep infections

38
Q

nephrotic and nephritic sediment are sx of

A

glomerulonephritis

39
Q

glomerulonephritis - metabolic _____

A

acidosis

40
Q

edema and stretching of the renal capsule lead to

2

A
  1. flank pain

2. back pain

41
Q

glomerulonephritis urinalysis results

4

A
  1. proteinuria
  2. hematuria
  3. erythrocyte casts
  4. no infection
42
Q

nephrotic syndrome hypoalbuminemia level

A

< 3.5g/dL

43
Q

nephrotic or nephritic syndrome - hematuria

A

nephritic

44
Q

glomerulonephritis mechanisms of injury - type II hypersensititivty (cytotoxic)

A

Abs reacting in situ against planted Ags within the glomerulus

45
Q

glomerulonephritis BP

A

elevated

46
Q

azotemia is to

A

nephritic syndrome

47
Q

most common cause of glomerulonephritis

A

immunologic abnormalities

48
Q

glomerulonephritis blood tests results reveal decreased what

1

A
  1. complement levels
49
Q

glomerulonephritis manifestations include

9

A
  1. hematuria
  2. RBC casts
  3. proteinuria
  4. macroalbuminuria
  5. oliguria
  6. HTN
  7. edema
  8. nephrotic sediment
  9. nephritic sediment
50
Q

glomerulonephritis mechanism of injury - type III hypersensitivity

A

deposition of circulating soluble Ag-Ab complexes, often with complement fragments

51
Q

hematuria with dysmorphoc RBCs and RBC casts

A

nephritic syndrome

52
Q

dark and cloudy urine is to

A

glomerulonephritis

53
Q

nephrotic syndrome findings include

5

A
  1. hypoalbuminemia
  2. edema
  3. hyperlipidemia
  4. lipiduria
  5. vitamin D deficiency
54
Q

nephrotic or nephritic syndrome - proteinuria < 3 g

A

nephritic

55
Q

nephritic syndrome - hematuria

2

A

dysmorphic RBCs, RBC casts also

56
Q

azotemia

A

high nitrogen compounds in blood

57
Q

glomerulonephritis - flank and back pain from

2

A
  1. edema

2. stretching of renal capsule

Pathophysiology - Final Exam (26 decks)

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