8. Hypertension Flashcards
What is the equation for MAP?
MAP= (SP+(2 X DP))/3
What are possible causes of secondary hypertension?
endocrine disorders preeclampsia neurogenic hypertension endocrine tumours aortic coarctation
Which drugs can induce hypertension? 2
amphetamines
steroids
What does hypertension increase the risk of?
stroke
coronary events
heart failure
renal failure
What are the symptoms of hypertension?
none!
headaches
dizziness
flushing
Two mechanisms for controlling blood pressure?
- baroreceptor reflex/sympathetic NS
2. ECF volume/plasma renin activity
Which drugs can reduce cardiac output?
diuretics
ACE inhibitors
Angiotensin II receptor antagonists
Beta blockers
Which drugs can reduce TPR?
Calcium channel antagonists
α-adrenoceptor blockers
ACE inhibitors
Angiotensin II receptor antagonists
ACE inhibitors examples? 2
enalapril
lisinopril
Angiotensin II receptor antagonist examples?
iosartan
valsartan
Calcium channel antagonists?
nifedipine
amlodipine
Thiazide diuretic
bendroflumethiazide
Beta Blocker
atenolol
α1 selective agents
prazosin
