8 - LH Surge Flashcards
When does oogenesis and oocyte maturation occur
Throughout the life of the female
- prenatal period
- neonatal period
- adult (post LH surge period)
What occurs in the prenatal/neonatal period of oogenesis
Germ cells undergo mitosis and become oogonia, then primary oocyte that begins meiotic prophase but then hits nuclear arrest
What parts of oogenesis occur after puberty
After LH surge, meiotic inhibitors are removed
Primary oocyte nucleus splits, one becoming a polar body, the other becoming the secondary oocyte
Ovulation can occur, plus fertilization = zygote
Slide 8
Diagram of oogenesis
What happens in the postnatal stage of oogenesis
Growth and zona pellucida forms
Slide 9, 10
Nuclear arrest and removal of it*
Important events in removal of meiotic arrest
- oocyte maturation inhibitor decreases
- maturation promoting factor acts on the germinal vesicle
- gap junctions (inhibitors keeping nucleus intact) break down
Slide 11, 12
Ovary super important
Overview of oocyte and follicle development
What stages of follicle development contain a primary oocyte
Primordial follicle to graafian follicle
Role of PGF2a in ovulation
- contractions of ovarian tissue
- release of lysosomal enzymes to breakdown the follicle and cause ovulation
Role of PGE2 and histamines in follicle remodeling ovulation
- increase blood flow
- increase fluid accumulation in the ovary & dominant follicle
During follicle remodeling and ovulation, what are the theca cells doing
Begin to express P4 instead of T4
P4 induces collagenase production by theca to breakdown connective tissue (epithelium of ovary)
Slides 14-16
Important *ovulation
What is the corpus hemorrhagicum
Structure that is left after ovulation (rupture). Associated with bleeding
Two types of ovulators
- spontaneous ovulators
- reflex (induced) ovulators
