Haematology 6: Venous Thrombosis Flashcards
1
Q
List 4 anticoagulant molecules expressed by the endothelium ?
A
TFPI
Thrombomodulin
EPCR
Heparans
2
Q
When using unfractionated heparin, how could you measure the level to see if the treatment is in the therapeutic window ?
A
APTT
anti-Xa assay
3
Q
Which DOAC inhibits factor IIa ?
A
Dabigatran
4
Q
Which DOACs inhibit factor Xa ?
A
Rivaroxiban
Apixaban
Edoxaban
(They have an X in the name)
5
Q
What reading is INR derived from ?
A
PT
6
Q
Can Warfarin be given during pregnancy ?
A
No its teratogenic
7
Q
Which factors are inhibited by Warfarin ?
A
10
9
7
2
Protein C and Protein S
Remember 1972
8
Q
List 5 risk factors for thrombosis ?
A
Cancer Surgery Obesity Elderly Immobility
9
Q
Which of these factors are associated with a higher risk of recurrence of DVT ?
Male sex Female Sex Proximal thrombosis Distal thrombosis Post surgery Idiopathic
A
Male sex
Proximal Thrombosis
Idiopathic
