Small Intestine Structure and Function Flashcards

1
Q

what is the total length of the small intestine?

A

around 6 metres

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2
Q

how long is the duodenum?

A

25 cm

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3
Q

what is the functions of the duodenum?

A

Gastric acid neutralisation; Digestion; Iron absorption

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4
Q

how long is the jejunum?

A

2.5m

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5
Q

what is the function of jejunum?

A

nutrient absorption

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6
Q

how long is the ileum?

A

3.5m

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7
Q

what happens in the ileum?

A

nacl/h2o absorption -> chyme dehydration

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8
Q

how is the absorptive surface area enhanced?

A

by folds, villi and microvilli

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9
Q

what has the best absorptive surface area enhancement?

A

microvilli

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10
Q

what do villus cells absorb?

A
NaCl
Monosaccharides
Amino acids
Peptides
Fats
Vitamins
Minerals
Water
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11
Q

what is the function of a crypt cell?

A

secretes cl and water

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12
Q

what can be coupled withsodiem in active transport?

A

glucose
galactose
amino acids
nucleosides

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13
Q

how much water does the small intestine secrete a day?

A

1500ml

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14
Q

why is water secretion important for normal digestive processes?

A

Maintains lumenal contents in liquid state

Promotes mixing of nutrients with digestive enzymes

Aids nutrient presentation to absorbing surface

Dilutes and washes away potentially injurious substances

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15
Q

what is the two disticnt types of movement?

A

segmentation

peristalsis

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16
Q

when is segmentation most common?

A

during meals

17
Q

what is the function of contraction and relaxation of short intestinal segments?

A

moves chyme into adjacent areas of relaxation, then relaxed areas then contract and push chyme back.

this ensures thorough mixing of contents with digestive enzymes

18
Q

what are segmented contractions initiated?

A

depolarisation generated by pacemaker cells in longitudinal muscle layer

19
Q

what is the fequency of segmentation determined by?

A

basic electrical rhythm

20
Q

what effects does parasympathetic ns have on contractions?

A

increases

21
Q

what efects does sympathetic ns have on contractions?

A

decreases

22
Q

whats the function of migrating motility complex?

A

Move undigested material into large intestine

Limit bacterial colonisation of small intestine

23
Q

what hormone is involved in initiating migrating motility complex?

A

motilin

24
Q

what nuerones mediate peristalsis of intestine?

A

myenteric plexus

25
Q

what effect does gastric emptying have on segmentation activity in ileum?

A

increases

26
Q

what effects does gastric emptying have on gastroileal reflex?

A

Opening of ileocaecal valve (sphincter)

Entry of chyme into large intestine

Distension of colon

Reflex contraction of ileocaecal sphincter (prevents backflux into small intestine)