Week 4: Congenital Infections Part II Flashcards
1
Q
CHEAP TORCHES LZ
A
2
Q
Common clinical manifestations of intrauterine infections
A
- Low birth weight (SGA)
- Possible malformation
- Rash
- Jaundice/direct bilirubin
- Hepatosplenomegaly
- Anemia, low platelets
- Stable
- or Asymptomatic
3
Q
Common clinical manifestations of Perinatal infections
A
- Normal weight (AGA)
- No malformations
- Sepsis Syndrome
- Coagulopathy/DIC
- Hepatitis
- Conjunctivitis
- Sometimes clinically unstable (sepsis)
- or Asymptomatic
4
Q
Causative organisms of in utero infections
A
- HIV
- CMV
- HSV
- Toxoplasma
- Syphilis
- Rubella
- LCMV
- Parvovirus B19
- Zika virus
5
Q
Causative organisms of Perinatal infections
A
- HIV
- CMV
- HSV
- VZV
- Enterovirus
- GC/Chlamydia/HPV
- Hepatitis B/C/E
- E coli/GBS/Listeria
6
Q
Causative organisms of Post-natal infections
A
*Breastfeeding*
- HIV
- CMV
- Hepatitis B virus
7
Q
Signs and symptoms of congenital/perinatal Rubella
A
- Sensorineural deafness
- Cataracts
- Congenital heart disease
8
Q
Signs and symptoms of congenital/perinatal Toxoplasma gondii
A
- Hydrocephalus
- Diffuse Intracranial calcifications
- Chorioretinitis
9
Q
Signs and symptoms of congenital/perinatal CMV
A
- Microcephaly
- Perinatal intracranial calcifications
10
Q
Signs and symptoms of congenital/perinatal Parvovirus B19
A
- Diffuse edema (hydrops fetalis)
11
Q
Signs and symptoms of congenital/perinatal VZV
A
- Limb abnormalities
- Cicatricial lesions
12
Q
Signs and symptoms of congenital/perinatal Treponema pallidum
A
- Skin lesions (including palms and soles)
- Dactylitis, osteochondritis periostitis
- Rhinorrhea (snuffles)
13
Q
Signs and symptoms of congenital/perinatal HSV
A
- Vesicular lesions
- Keratoconjunctivitis
14
Q
For congenital infections consider
A
15
Q
Case 1 Hx
A
16
Q
Case 1 Hx
A
17
Q
Question
A
