13. Genetics of Common and Complex Disease Flashcards
1
Q
What is the incidence rate of rare diseases?
A
<1/2000
2
Q
What is the GWAS study design?
A
Tests frequent SNPs amongst a large number of those both afflicted with illness and controls
DNA array hibridization chips can show SNPs in parallel
P-values used to test for statistical significance
3
Q
What is an odds ratio?
A
Represents odds that a disease will occur given a certain genotype, compared to the odds of it occurring in the genotype’s absence
