Blood Flashcards

1
Q

blood consists of

A

formed elements and plasma

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2
Q

plasma is

A

55%

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3
Q

formed elements

A

45%

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4
Q

plasma composed of

A

92% water, 6% proteins ( albumin, globulins, transferrin and fibrinogen) and ions, nutrients, gases, waste

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5
Q

formed elements

A

majority RBC, then WBC, and platlets

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6
Q

major contributor to colloid pressure of plasma

A

albumin

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7
Q

fibrinogen function

A

form fibre threads to blood clot

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8
Q

where are plasma proteins produced

A

liver

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9
Q

what is spectrin

A

cytoskeleton protein that binds to cytosolic side of membrane protein t, responsible for elastic strength in RBC

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10
Q

maturation of RBC takes

A

4 days

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11
Q

all blood cells are derived from

A

hematopoietic stem cells (hemocytoblasts)

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12
Q

stages of RBC

A

hemocytoblast –> basophilic erythroblasts, polychromatic erythroblasts, then lose nun to become reticulocytes

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13
Q

what creates platlets

A

fragments of egakaryocytes

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14
Q

leukopenia

A

reduction of WBC

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15
Q

reduction of RBC

A

aplastic anemia

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16
Q

destruction of RBC

A

in spleen and liver –> phagocytosis

17
Q

PCV

A

% of RBC

18
Q

normal democrat

A

45% men, 42% women

19
Q

polycythemia

A

high PCV

20
Q

neutrophils

A

phagocytic cells

migrate out of BV and enter tissue

21
Q

eosinophils

A

protect against parasites, and allergies, release anti-inflammatory substances

22
Q

basophils

A

histamine and heparin release

23
Q

hemostasis

A

stoppage of blood flow

- platelets release platelet factors, attract more and clog wound

24
Q

blood clotting mechanism

A
  1. release clotting factors
  2. formation of thrombin by prothrombin factor and calcium acting on prothrombin
  3. thrombin forming fibrin from fibrinogen
25
Q

how is blood type named

A

according to the type of antigen on the RBC

26
Q

anti- RH antibodies can appear when?

A

if mother is Rh negative, comes in contact with RH positive RBC, mother will produce anti RH antibosies, can be fatal if she has another RH positive baby