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Respiratory Medicine > Interstitial Lung Disease > Flashcards

Interstitial Lung Disease Flashcards

1
Q

What is interstital lung disease?

A

Wide spread lung fibrosis

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2
Q

What can cause ILD?

A 
Occupational 
- fumes 
- asbestos 
Sarcoidosis 
SLE 
Amyloidosis
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3
Q

What happens in fibrosis?

A

Replacement of damaged cells
- injured with inflammation

Focal fibrosis = response to irritants

Diffuse parenchymal diseae

  • occurs with idiopathic lung disease
  • extrinsic allergic alveolitis
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4
Q

What can cause upper-middle zone ILD?

A 
Aspergillosis 
Pneumoconiosis 
Extrinisic allergic alveolitis 
Negative sero arthropathies 
TB
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5
Q

What can cause mid-lower zone?

A 
Sarcoidosis 
Toxins 
Asbestosis 
Idiopathic pulmonary fibrosis 
Rheum
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6
Q

What is idiopathic pulmonary fibrosis?

A

Lungs enter pro-inflammatory state driven by macrophages and fibroblasts

Promotes fibrosis and destruction of alveoli

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7
Q

What is the spirometry patter of idiopathic pulmonary fibrosis?

A

Restrictive

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8
Q

What is the presentation of ILD?

A

SoB
Dry cough
Inspiratory fine crackles
Clubbing

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9
Q

What is the spirometry pattern of ILD?

A

Restrictive pattern

Reduced FVC
Normal FEV-1

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10
Q

What investigations would you do for ILD?

A

Bloods

  • FBC
  • U+Es
  • CRP

CXR

HR-CT

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11
Q

What would the CXR show?

A

Reduced lung volume

Increased lung markings

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12
Q

What would the HRCT show?

A

Honeycomb sign

- large airspaces with fibrotic walls

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13
Q

How is ILD managed?

A

Pulmonary rehab
Smoking cessation

Acute exacerbation = corticosteroids

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14
Q

What is extrinsic allergic alveolitis?

A

Hypersensitivity reaction caused by inhalation of allergens

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15
Q

What can cause EAA?

A

Bird fancier’s lung
Farmer’s lung
Malt worker’s lung

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16
Q

What are the acute clinical features of EAA?

A 
Fever
Rigors
Myalgia 
Dry cough 
Dyspnoea
17
Q

What are the chronic clinical features of EAA?

A

Increasing dyspnoea
Weight loss
Type 1 respiratory failure

18
Q

How is EAA managed?

A

Allergen avoidance

Steroids

Respiratory Medicine (18 decks)

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