Dexamethasone Flashcards
1
Q
Presentation
A
8 mg in 2 ml glass vial
2
Q
Pharmacology
A
Cortiocosteroid secreted by the adrenal cortex
Actions:
- Relieves inflammatory reactions
- Provides immunosuppression
3
Q
Metabolism
A
- by the liver and other tissues
- excreted predominantly by the kidneys
4
Q
Indications
A
- Bronchospasm associated with acute respiratory distress not responsive to nebulised salbutamol
- Moderate - severe croup
- Acute exacerbation of COPD
5
Q
Contras
A
Known hypersensitivity
6
Q
Precautions
A
Solutions which are not clear or are contaminated should be discarded
7
Q
Route of administration
A
IV (administered over 1-3 minutes)
Oral
8
Q
Side effects
A
Nil of significance in the above indication
9
Q
Special notes
A
Does not contain an antimicrobial agent, therefore use solution immediately and discard any residue
10
Q
IV effects
A
Onset: 30-60 mins
Peak: 2 hours
Duration: 36-72 hours
11
Q
Severe asthma
A
8 mg IV/Oral single dose only
12
Q
COPD
A
8 mg IV/Oral single dose only
13
Q
Croup
A
600 mcg/kg Oral (max 12 mg) - single dose only
