Dextrose 10%

Question 1

Presentation

Answer 1

25 g in 250 ml infusion soft pack

Question 2

Pharmacology

Answer 2

Slightly hypertonic crystalloid solution

Composition:

• Sugar - 10% dextrose
• Water

Actions:

• Provide a source of energy
• Supplies body water

Question 3

Metabolism

Answer 3

Dextrose:

• Broken down in most tissues
• Stored in the liver and muscle as glycogen

Water:

• Excreted by the kidneys
• Distributed throughout total body water, mainly in the extracellular fluid compartment

Question 4

Indications

Answer 4

diabetic hypoglycaemia (BGL <4mmol/L) in pts with an altered GCS and unable to self-administer oral glucose

Question 5

Contras

Answer 5

NIL of significance in the above indication

Question 6

Precautions

Answer 6

NIL of significance in the above indication

Question 7

Route of administration

Answer 7

IV infusion

Question 8

Side effects

Answer 8

NIL of significance in the above indication

Question 9

IV effects

Answer 9

Onset: 3 mins
Peak: n/a
Duration: Depends on severity of hypoglycaemic episode

Question 10

Hypoglycaemia

Answer 10

BGL < 4 mmol/L and not responding to commands

• IV cannula in a large vein
• Confirm IV patency
• 15 g (150 ml) followed by a 10 ml flush

5-10 mins - If GCS or BGL not returned to normal:

• 10 g (100 ml) titrated to effect
• followed by a 10 ml flush