Microbiology 1 - Hospital acquired infection Flashcards

1
Q

What if the most common disease caused by an HAI?

A

Hospital acquired pneumonia

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2
Q

What type of bacteria is c. difficile?

A

Gram pos spore-forming anaerobe

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3
Q

Name the toxins produced by c. difficile

A

Toxins A and B

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4
Q

What are the symptoms of C. difficile infection?

A

Diarrhoea

Colitis

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5
Q

Name 2 Antibiotics that are used to treat C. difficile?

A

Metronidazole

Vancomycin

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6
Q

What type of bacteria is vancomycin effective against?

A

Gram pos

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7
Q

What is the pathognemonic endoscope finding for C diff infection?

A

Columns of inflammatory exudate in colon lining

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8
Q

How should C diff infection be managed?

A
  1. Stop antibiotics
  2. Fluid + electrolyte resuscitation for patients with diarrhoea
  3. ORAL vancomycin/ metronidazole to combat C. diff
    Other options (but are VERY ££££££) are fidaxomicin or bezlotoxumab OR faecal transfer
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9
Q

What are the most common causative pathogens in HAP?

A

S aureus
Klebsiella
Pseudomonas
Haemophilus

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10
Q

Which 3 antibiotics can predispose you to C diff infection?

A

Cephalosporin
Clindamycin
Ciprofloxacin

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