Microbiology 3 - Antimicrobial Agents 2 Flashcards

1
Q

What mnemonic can be used to help decide which antibiotic to use?

A
CHAOS
Choice depends on the: 
Host charcteristics 
Antimicrobial susceptibilities of the
Organism itself, as well as the
Site of infection
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2
Q

What is the Minimum Inhibitory Concentration and Breakpoint of an antibiotic useful for?

A

Working out sensitivity
MIC > breakpoint = resistant
MIC < breakpoint = sensitive

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3
Q

What antibiotic should be given for gram pos cocci in clusters?

A

Flucloxacillin

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4
Q

What antibiotic should be given empirically for gram neg cocci?

A

Ceftriaxone (could be meningococcus)

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5
Q

What is the “eagle effect”?

A

Increasing the penicillin dose –> decreasing antibacterial activitity after a point

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6
Q

How does the choice of antibiotic to treat UTI differ between community and hospital?

A

Community: nitrofurantoin/ trimethoprim
Hospital: cephalexin/ augmentin

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