Splenomegaly Flashcards
1
Q
most frequent causes of splenomegaly
A
- reactive reticulo-endothelial hyperplasia in pts with chronic hemolytic anemia
- lymphoid hyperplasia in spleen in pts with lymphoma
- neoplastic proliferation of lymphoid cells
- myelofibrosis
- metastasis
- vascular congestion in liver cirrhosis
2
Q
classification of splenomegaly according to etiopathogenesis
A
- congestive
- infectious
- inflammatory
- infiltrative/neoplastic
- infiltrative/non neoplastic
- RBC destruction (chronic hemolytic anemia)
- structure
3
Q
repercussions on the CBC profile of hypersplenism
A
anemia, bleeding (thrombocytopenia), and infections (neutropenia)
- pancytopenia
- compensatory bone marrow hyperplasia
4
Q
repercussions on the CBC profile of splenectomy
A
transient leukocytosis, thrombocytosis. Hypo-splenism could be a late consequence
5
Q
pre splenectomy procedure you must give which vaccines
A
pneumococcum
streptococcum
6
Q
indications for splenectomy
A
- splenic trauma with splenic disruption
- splenomegaly in myelofibrosis
- hereditary spherocytosis
- rare lymphoma
