Non Hodgkin Lymphoma Flashcards
1
Q
how do we classify lymphoid malignancies
A
as B cell derived (are 70% of all NHL) or T cell derived (associated with angineural lymphoma)
2
Q
clinical features of NH lymphomas
A
B symptoms, nausea, compression syndromes, SVC syndrome, dyspnea, orthopnea, refractory pruritus
3
Q
diagnostic pathway of NHL
A
- excisional biopsy or FNA for lymph nodes
- immunophenotype
4
Q
main therapeutic options of NHL
A
- radiation
- bone marrow biopsy
- chemo (RCHOP), monoclonal antibodies, radiotherapy
5
Q
which is more common HL or NHL
A
NHL is 5x more common than HL
6
Q
an elevated LDH means
A
poor prognosis
7
Q
chromosome in mantle cell lymphoma
A
ch 11 gene or cyclin D1 protein and ch 14 for immunoglobulin heavy chain
