Lecture 6

Question 1

what is medical cannibas benefical for?

Answer 1

• antispasmodic for mutiple sclerosis
• anti seizure for some forms of epilepsy
• anti emetic for the treatmnet of chemotherapy - induced nausea
• glaucoma

Question 2

What are three benefical products of cannibas

Answer 2

1- cannabinols
2- cannabidiol
3- terpenes

Question 3

where does cannibas come from?

Answer 3

• lake quinghai in central china 19.6 million years ago

Question 4

hemp fibre

Answer 4

• tough and light
• was used by steppe nomads initally to make horsetails and then ropes and cloth
• covering of wagons

Question 5

what did people in history use cannibas for?

Answer 5

• Archeologists generally think that cannabis was used at least for its fiber by Paleolithic and Neolithic
people.
• It appears that Cannabis originated in the Eurasian
Steppes

Question 6

where was cannibas found in china, turpan?

Answer 6

Cannabis has been found buried with a Indo-European shaman of the Yanghai
culture in a tomb in China from 2500-2800 years ago, part of a group of people described as “blue-eyed and blond-haired”. Nearly a kg of plant matter, initially thought to be coriander, turned out to be cannabis.

Question 7

Cannibas in India

Answer 7

• Atharva Veda mentions cannabis as one of the five most sacred plants on earth and says the guardian angel resides in the leaves
• cure diseases of the nervous system and an antispasmodic and anticonvulsive

Question 8

Cannabis medical uses in the 1800s

Answer 8

• Clouston TS (1870) found evidence that Cannabis was an effective treatment for insanity, especially in combination with potassium bromide
• Opium, strong beef tea and scotch whisky (considered to be a stimulant by the Scots) were ineffective.

Question 9

what were thought to be active ingrediants of cannabis

Answer 9

• purified red oil

- cannabidiol

Question 10

what happens when purified red oil is adiminsterd in dogs

Answer 10

Purified red oil, when administered intravenously into dogs, was observed to induce ataxia (lack of muscle control or coordination of voluntary movements, such as walking or picking up objects), and this became accepted as a test for the cannabis active ingredient at the time of Adams.

Question 11

how is Cannabioal thought to help people

Answer 11

There is conflicting evidence that very high doses (> 1-2 grams/day) may reduce psychotic symptoms in
schizophrenia, although some studies show no differences from placebo
• There is better evidence that it can reduce convulsive
seizures in children with a rare form of childhood epilepsy, Dravet syndrome