GI 3: Digestion & Absorption of Lipids Flashcards

1
Q

what makes the digestion / absorption of lipids a complex process?

A

lipids are not water-soluble

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2
Q

what is the main source of dietary lipids?

A

triglycerides

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3
Q

what are triglycerides made of?

A

glycerol and 3 fatty acids

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4
Q

what enzymes in the mouth, stomach and pancreas can be used to digest lipids>

A

lipase and collapse

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5
Q

collapse acts as an ___

A

anchor

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6
Q

____ are essential for emulsification and micelle formation

A

bile salts

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7
Q

what is emulsification?

A

division of large lipid droplets into small droplets by bile salts to improve lipid digestion

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8
Q

which has a great effect of lipid digestion, lingual and stomach lipase or panreatic lipase?

A

pancreatic

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9
Q

what is the lipid process before digestion?

A

emulsification

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10
Q

what is the lipid process after digestion?

A

micelle formation

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11
Q

bile salts are amphipathic, which means

A

the have both a hydrophobic and hydrophilic part

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12
Q

after emulsification, triglycerides are available to ___ and __ and are digested into ___ and ___

A

lipase and collapse,; monoglycerides and fatty acids

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13
Q

a small amount of monoglycerides enter enterocytes by ___ by a -___ (slow/fast)

A

diffusion; slow

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14
Q

what is a micelle and its role?

A

very small droplets that hold MG and FA close to enterocytes until they are ready for absorption

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15
Q

as the concentration of FA/ MG decreases , some micelle compounds will ___

A

leave and enter by diffusion

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16
Q

absorbed fats combine with cholesterol and proteins in the enterocytes to form ____

A

chylomicrons

17
Q

chylomicrons are removed by the ___ system

A

lymphatic

18
Q

once in the enterocyte, FA and MG reform to make ___

A

triglycerides

19
Q

chylomicrons diffuse into the ___ of the lymphatic system

A

lacteal

20
Q

how do chylomicrons cross the basolateral membrane?

A

by exocytosis

21
Q

in the fed state, absorption of chylomicrons can be easily seen in intestinal lacteals that look ___

A

milky

22
Q

bile salts remain in the ___, ___% are re-absorbed in the ileum and transported back to the ___ for recycling

A

lumen, 95, liver

23
Q

a decrease in bile cycling would result in ____ cholesterol ratio in the bile, resulting in ___

A

increased; galstones