Cancer Flashcards

1
Q

normal cells vs cancer cells

A
uniform shape vs abnormal
cell cohesive vs not
controlled growth vs rapid and disorderly
well differentiated vs poorly
mortal vs. immortal
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2
Q

Who is at risk for cancer?

A

People with immune-compromised d/t inability to get rid of tumor-assoc. antigens.

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3
Q

What labs to monitor?

A

Oncofetal

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4
Q

Dx/Classification?

A
H/P
Diagnostic studies
radiology studies
lab studies
bone marrow exam
biopsy
classification
anatomic site classification
histology classification
extent of disease classification (higher the grade, higher the risk)
TMN classification (0-4)
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5
Q

Nurse intervention fators

A

Screenings, don’t smoke, sunscreen, reduce stress, diet, limit red meat and salt cured meat, limit smoked meat, exercise, normal body weight

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6
Q

Warning Signs of Cancer

A

C - change in bowel or bladder habits.
A - sore that does not heal
U - Unusual bleeding or discharge from any body orifice
T-thickening of lump in breast or elsewhere
I- Indigestion or diff. swallowing
O- Obvious change in a wart or mole
N - nagging cough or hoarseness

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7
Q

Goal of cancer treatment

A

Cure
Control (can’t cure, but maintain)
Palliation (relief of sx)

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8
Q

Treatment includes…

A
Chemo/radiation
Surgical
Immunotherapy
Targeted (specific per type of cancer)
Hormone therapy
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9
Q

Surgery

A

Surgical: prevents/cures/controls. Supportive and Palliative.

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10
Q

Chemotherapy

A

Oral/Intravenous
Regional chemo admin (intraarterial, intraperitoneal, intrathecal, intraventricular, intravesicular)
Effects of chemotherapy on normal tissues…extravasation!!

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11
Q

Radiation

A

External Beam or Internal Beam (Bracytherapy)

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12
Q

External Beam vs. Internal Beam

A
  • Patient NEVER radioactive vs. IS radioactive.
  • local treatment and site marked vs. implantation or insertion of radioactive material.
  • Internal: HDR/LDR

ALERA!!! As Low As Reasonable Achievable (exposure for nurse). This is determined by radiation safety officer.

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13
Q

Nursing Management for radiation and chemotherapy

A

Bone Marrow Suppression = Nadir…neutropenia (neupogen and neulasta) /thrombocyt (neumega) / anemia (Procrit)
Nadir is lowest 10-14 days post treatment.

Fatigue (anemia??)

  • lack of sleep
  • anxiety
  • dehydration
  • activity helps…nurse intervention!

GI Effects

  • nausea/vomit
  • diarrhea
  • mucositis
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14
Q

What to monitor?

A
dehydration, fatigue, electrolytes! 
Nausea/vomiting/diarrhea
(Antiemetic)
...low fiber! 
Hydration may be necessary...even just coming in for IV. 
Skin breakdown in Perineum! 
Mucositis- effected by dry mouth. 
Loss of taste, painful swallowing, esophagitis...
Monitor for oral thrush!! 
Anorexia...

monitor labs!
-albumin, weight loss, electrolytes.

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15
Q

Management

A

Reproductive - chemo leads to fertility issues.
Pulmonary - SOB/dyspnea/side affect of tx?
Cardio - cardiac toxicity! HF!
Cognitive - Chemo brain is real.

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16
Q

Skin Reactions

A

Prevent Infection and promote wound healing!
Desquamation
-no temp extremes, no tight garments, no harsh chemicals or materials,
-perfume-free lotion…
-no saltwater/chlorine, no shaving armpit
-mild washing and expose to air.
-no sun exposure.

17
Q

Hematopoietic Stem Cell Transplantation

A

Eradicate cells so bone marrow can produce more. (very immune-compromised) And then utilize stem cells to overtake cancer.

Allogenic (acquired from donor)
Syngeneic (twin)
Autologous (get own stem cells back after chemo)

18
Q

Complications

A

Nutrition

  • disgeusia (bad taste)
  • cachexia (wasting/wt loss)

Infection
-leading cause of death

Pain

  • ask about pain
  • breakthrough pain
  • precipitates pain?
  • antidepressants
  • nonpharmacologic measures (homeopathic.
19
Q

Ontologic Emergencies

A

Obstructive

  • spinal cord compression (pain!!)
  • superior vena cava syndrome)

Metabolic
-ADH (water retention, seizures, hyponatremia)

Infiltrative

  • Cardiac Tamponade
  • Carotid Artery Rupture
20
Q

Coping w/ Cancer

A

Fear
Depression
Lack of Hope

21
Q

The nurse is admitting an oncology patient to the unit prior to surgery. The nurse notes that the patient has just finished radiation therapy to the chest. The nurse should prioritize assessments related to which potential health problem?

A

Impaired wound healing

22
Q

The nurse is caring for a patient on the Bone Marrow Transplant Unit who received an allogeneic stem cell transplant 1 week ago. The nurse assesses for Graft vs Host Disease by assessing for:

A

Abdominal Pain
Blistering of the skin
Desquamation of the palms
Diarrhea

23
Q

A patient is receiving Adriamycin to treat his non-Hodgkin’s lymphoma. The nurse is reviewing the patient’s laboratory results. Which of the following results would indicate the patient could be experiencing tumor lysis syndrome?

A

Elevated phosphate level
Decreased Calcium Level
Increased Potassium Level