A&P Ch 4 Flashcards
genetics & cellular function (44 cards)
nucleic acid structure
nitrogenous base (AGCUT), sugar (DNA=deoxyribose, RNA=ribose), phophate
nitrogenous base
purines=AG, pyrimidines=CUT
purines
A=adenine, G=guanine
pyrimidines
C=cytodine, U=uracil, T=thymin
dna structure
double stranded, twisted ladder, backbone is formed of sugar and phosphate, complementary base pairing A-T, C-G. held together with hydrogen bond
dna function
dna-rna-protein, dna holds the instructions, proteins build the organism
chromatin
dna+histones coiled together into nucleosomes and looped. to prepare for division, the chromatin loops again (condenses)
rna structure and function
mrna-> protein. single stranded. mrna, rrna, trna
mrna
only lasts a couple hours, carries messages from dna to ribosomes
rrna
makes up ribosome along with proteins
trna
carries amino acids to ribosome to make protein
gene
unit of heredity contained on a chromosome. sequence of dna that can be transcribed to rna and usually translated to a protein
human genome
all the dna sequences in one set of chromosomes. 23 pairs of chromosomes.
genetic code
the 4 dna nucleotides are arranged in groups of 3=base triplet. base triplet -> codon (mrna) via transcription. codon->amino acid(protein) via translation. 64 possible codons. 60 code for 20 amino acids, 3 code for stop and 1 codes for start
transcription
dna->pre-rna. rna polymerase. pre-rna->mrna. happens in nucleus
translation
mrna->protein. ribosomes. happens in the ribosome. trna brings one amino acid at a time to growing polypeptide. polyribosomes speed the process.
gene regulation
any one cell only uses a fraction of the genome. any one part of the genome may only be used at particular times
dna replication
photocopying instruction book. cell replicates dna for growth, repair and maintenance. epithelial cells divide most. dna unwinds from histones, helicase opens helix, polymerase makes complementary strand, dna is rewound into chromatin
cell cycle
g1, s, g2, m, cytokinesis, g0
g1
first gap, growth and normal metabolic roles
s
synthesis, dna replication, organelles double
g2
2nd gap, growth and prep for mitosis
m
division of dna
cytokinesis
division of everything else