A&P1_HW04 Flashcards
(32 cards)
What events can result in a protein misfolding?
- a mutation in a gene that changes an amino acid in a protein
- a protein adopts a stable but nonfunctional tertiary structure
- contact with a misfolded protein with the same amino acid sequence
Name __ types of motor proteins
- myosin
* dynein
Plasma membranes are selectively permeable, or semipermeable, meaning that
the membrane regulates what enters and leaves the cell.
Describe diffusion
The movement of a substance from a region where it is more concentrated to a region where it is less concentrated, down its concentration gradient.
Define the cell membrane’s role in homeostasis
If there is an excess of carbon dioxide inside the cell, some of the carbon dioxide molecules permeate the membrane and leave the cell.
Passive forms of transport move molecules such as water across the cell membrane with no energy added.
Describe a Simple diffusion
movement of solute out of the cell directly through the plasma membrane
Describe a Facilitated diffusion
movement of solutes out of the cell down their concentration gradient using membrane proteins
Describe a Active transport
movement of solute out of the cell against their concentration gradient using membrane proteins
Describe a Bulk transport
movement of contents of transport vesicles out of the cell by exocytosis
Substances that move easily through the lipid bilayer of the plasma membrane
Small, uncharged molecules, such as oxygen can pass easily between the phospholipids in a plasma membrane because they do not interact with the hydrophobic fatty acid tails of the phospholipid molecules
Substances that need help from a protein to cross the membrane because they are repelled by the lipid bilayer
- large polar molecules, such as the simple sugars frutose and glucose, are not only too big to squeeze easily between the phospholipids, they are repelled by the hydrophobic fatty acid tails of the the phospholipid that make the middle of the lipid bilayer.Likewise, many of the amino acids are charged or polar, and they have difficulty passing between the phospholipid tails. Protein channels allow these molecules to cross the membrane.
- charged substances are repelled by the hydrophobic fatty acid tails of the phospholipid molecules and connot cross through the membrane without the help of a protein carrier. Ions, such as calsium ions, are very small, but they have troble moving across cell membranes with the help of protiens because it dissociates into two ions when in water
Describe passive transport
- does not require energy
* moves substances down a concentration gradient
Describe active transport
- requires energy
* moves substances against a concentration gradient
Describe simple diffusion
movement of solutes out of the cell directly through the plasma membrane
Describe facilitated diffusion
movement of solutes out of the cell down their concentration gradient using membrane proteins
Describe primary active transport
movement of solutes into the cell against their concentration gradient using ATP-powered membrane pumps
Describe secondary active transport
movement of one solute out of the cell, against its concentration gradient, via a cotransporter driven by another solute’s gradient
Define facilitated diffusion
a protien-faciliated movement of solutes across a membrane from an area of higher concentration to an area of lower concentration
Passive transport best describes
facilitated diffusion
What is an aquaporin?
membrane protein that contains a channel for water movement
Examples of facilitated diffusion
*an inner ear hair cell allows potassium ions to flow down their concentration gradient after sound waves stimulate a membrane protein
*a kidney cell absorbs water molecules down their concentration gradient using a membrane protein
A neuron allows potassium ions to leave the cell down their concentration gradient using a membrane channel
When a muscle contracts, calcium ions are forced into an extracellular space against their concentration gradient
An influx of ATP provides the energy needed for an ion pump
Example of symporter
A protein moves one H+ ion and one K+ ion out of the cell
Example of uniporter
A protein allows glucose to flow into a cell down its concentration gradient