A2 Biopsychology Flashcards

(94 cards)

1
Q

What are the strengths of localisation of function?

A

. Phineas gage ‘no longer gage’ after injury to frontal lobe

.brain scans- Peterson (1988) found only Broca’s area used in reading task and only wernickes area used in listening task

. Neurosurgical evidence- Dougherty (2002) put lesions in cingulate gyrus of OCD sufferers- 30% made full recovery, 14% made partial recovery

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2
Q

What are the limitations of localisation of function

A

Lashley’s rats- removed 10-50% of rats brains and no area affected them doing the maze more than others- shows their brains work holistically.

Plasticity- if brain undergoes trauma in some cases brain is able to reorganise itself to regain function- shows holism

Dick and Trembly- found only 2% of modern researches believe language is completely controlled by B and W areas- fMRI scans have showed language is holistic

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3
Q

What is hemispheric lateralisation

A

The idea that the two halves of the brain are functionally different and that each hemisphere has specific functions

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4
Q

Is language lateralised?

A

Yes- B and W areas are both in the left hemisphere

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5
Q

What side of the brain contributes to emotional context?

A

Right

RH is the synthesiser

LH is the analyser

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6
Q

Is movement lateralised?

A

No- but it is cross wired (contralateral wiring) RH controls movement on left and vice Versa

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7
Q

Is vision lateralised

A

No- it is both contralateral and ipsilateral each eye gets info from RVF and LVF and each is processed in the opposite side of the brain (LH or RH)

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8
Q

Outline Sperry’s experiment

A

Tested on 11 males with commissurotomy’s

Patients would stare at cross in the middle of a screen and either and image or a word would flash in the LVF and RVF

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9
Q

What were the findings of Sperry’s experiment

A

Describe what you see- when object or word was displayed in right RVF the patient could easily describe it as was processed in LH

Recognition by touch- although patients could not verbally say what they saw in LVF and processed in RH they could pick up the object they saw when presented with and array of different things- they could also select the most similar (cigarette- ashtray etc)

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10
Q

What were the findings of Sperry’s experiment

A

If word or object shown in RVF patient could easily say what it was as processed by LH. If object or word shown in LVF patient could not remember was they saw

Even though patients could not verbally describe stimulus in LVF they could pick up the object from behind a screen- they could also select object most similar to the one they saw (cigarette- ashtray etc)

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11
Q

What were the findings of Sperry’s research

A

If word or object shown in RVF patient could easily say what it was as processed by LH. If object or word shown in LVF patient could not remember was they saw

Even though patients could not verbally describe stimulus in LVF they could pick up the object from behind a screen- they could also select object most similar to the one they saw (cigarette- ashtray etc

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12
Q

What does Sperry’s research tell us about hemispheric lateralisation

A

RH is non verbal

LH is verbal

RH can still process information non verbally

When racy image showed in LVF patient would giggle even though they didn’t know what they saw

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13
Q

What are the strengths of hemispheric lateralisation

A

Highly scientific supporting evidence- Fink et Al (1996) identified with PET scans that during a visual task when an image was looked at holistically RH was more active but when asked to focus on details LH was more active

Real world applications- Gazzaniga found that spilt brain patients are better at identifying an odd one out in a group because LH has better cognitive abilities which are not interfered with by RH. Rogers showed chickens with spilt brains could feed and look for predators simultaneously.

High internal validity of evidence- Sperry’s experiment was highly controlled- cross used to focus on etc

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14
Q

What is a limitation of hemispheric lateralisation?

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Sperry’s research lacks generalisability- only carried out on 11 men all who previously had severe epilepsy

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15
Q

What is the definition of plasticity

A

Your brains ability to change and adapt as a result of new experiences and learning. As a child you have thousands of synapses per neuron but these are cut by ‘synaptic pruning’ suggesting your brain can change during adulthood.

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16
Q

What is the definition of functional recovery

A

When brain adapts to trauma by getting other parts of brain to carry out function of damaged part

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17
Q

Outline maguires study

A

Compared brains of black cab drivers to control group chosen by matched pairs design

Significantly more grey matter in posterior hippocampus of black cab drivers

Posterior hippocampus is for spatial awareness

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18
Q

What are the strengths of plasticity

A

Maguires experiment highly controlled- used matched pairs design and MRI scans to gather data

Draganski observed 3 medical students before and after exam and all 3 had either larger or more connections in posterior hippocampus and parietal cortex

Michelli found that people who were bilingual had bigger parietal cortex’s than people who weren’t

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19
Q

What are the strengths of plasticity

A

Maguires experiment highly controlled- used matched pairs design and MRI scans to gather data

Draganski observed 3 medical students before and after exam and all 3 had either larger or more connections in posterior hippocampus and parietal cortex

Michelli found that people who were bilingual had bigger parietal cortex’s than people who weren’t

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20
Q

What is a limitation of plasticity

A

Maguires results may not be reliable- none of the taxi drivers were tested before they took their ‘knowledge test’

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21
Q

How does Jody support idea of plasticity and functional recovery

A

Had RH removed at 3

LH took up all the function of RH

Can function almost perfectly with only slight paralysis on left side

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22
Q

What happens to the brain during recovery

A

New synaptic connections

Secondary neural pathways created

Axonal sprouting

Denervation super sensitivity

Recruitment of the homologous area

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23
Q

What are the strengths of functional brain recovery

A

Real work application- help people recover from strokes etc. strapping hand behind back ( constraint induced movement therapy)

Supporting evidence- Bezzola gave people aged 40-60 40 hours of golfing lessons and their brain structures changed

Schneider found that people who stayed in education for 16 years had 40% chance of recovering from traumatic brain injuries- if in education for under 12 years 10% chance of recovery

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24
Q

What is a limitation of functional recovery

A

Not always a good thing- phantom limb syndrome occurs when somatoes sensory area remains idle for too long and another part of the brain takes up its function

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25
What is a limitation of functional recovery
Not always a good thing- phantom limb syndrome occurs when somatoes sensory area remains idle for too long and another part of the brain takes up its function
26
How does an fMRI scan work
Measures changes of blood flow in brain using radio waves and a magnetic field. As a result of these changes in blood flow, researchers can produce a map showing which areas of the brain are being used
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What are the strengths of fMRI
No radioactive tracer (risk free) Clear, high resolution images Shows where functions are localised
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What are the weaknesses of fMRI
Very expensive Patient must remain still for long period of time (bad for children, ADHD and the elderly) Poor temporal resolution (5 second delay between event and imaging)
29
How does an EEG work
Measures electrical activity in the brain. Electrodes on the scalp pick up small electrical activity from functioning brain cells. When the signals from different electrodes are graphed over a period of time you get an EEG
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What are the strengths of EEG
Can be used to diagnose epilepsy, sleep disorders, Alzheimer’s High temporal resolution (detects electrical activity in under 1 second)
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What are the weaknesses of EEG
General measure- only picks up on groups of neurons firing electrical impulses not individual Researchers can find it hard to decipher when different but adjacent areas are firing
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How does an ERP work
Using an statistical averaging technique researchers can tease out all extraneous brain activity from original EEG leaving only the brain activity related to the presentation of a specific stimulus. What remains are event related potentials: types of brainwaves that are triggered by particular events. Research has revealed many different forms of ERP that can be linked to cognition or perception
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What are strengths of ERP
More specific than EEG readings Very good temporal resolution as derived from EEG
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What are the weaknesses of ERP
To be successful all interference must be eliminated Not standardised- lots of different ways it is done depending on the researches
35
How does a post mortem work?
Used to establish the underlying neurobiology of a particular behaviour. For example, researches study a person who displays interesting behaviour that could stem from brain damage. Then when the person dies they can examine their brain to see if they were right. An example of this is Broca and Tan
36
What are biological rhythms
Distinct patterns of changes in body activity that conform to cyclical time periods. For example the sleep-wake cycle. These cycles are influenced by endogenous pacemakers and exogenius zeitgebers.
37
What is a cycle that occurs ONCE every 24 hours called
Circadian rhythm
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What cycle takes more than 24 hours to complete
Infradian rhythm
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What is the name of a cycle that occurs more than once every 24 hours called
Ultradian rhythm
40
What is the sleep wake cycle
7.30 am melatonin secretion stops 9 pm melatonin secretion starts
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What is the body temperature cycle
4.30 am lowest body temperature 7pm highest body temperature
42
What is Sieffre’s cave study and what did it find out
Lived in a cave in the alps for 2 months and a cave in Texas for 6 months with no natural light and no alarm clock. He found that his natural biological rhythm remained at 24-25 hours and he woke up and fell asleep on a regular schedule.
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What does sieffres study tell us about EP and EZ
Our sleep wake cycle is mainly dictated by EP
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What was Folkard’s study
People had to live in cave with no natural light for 3 weeks and go to sleep at 11.45 and wake up at 7.45. Clock on wall completed full cycle in 22 hours not 24
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What were the findings of Folkards study and what did it show
Participants were unable to adjust showing EP are more influential
46
What are two strengths of circadian rhythms
Real world application- Boivin (1996) found that night shift workers lose concentration at around 6 am and are more prone to accidents so breaks and artificial sunlight can be used to help this Real world application- chronotheraputics can be implemented- aspirin better at preventing heart attacks if given late at night than earlier in the day
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What are two weaknesses of circadian rhythms
Lack of generalisability- people who volounteer to stay in caves for months or weeks are likely to be of a certain demographic and have similar characteristics- leaving many groups not represented Differences- Czeiser found that people have different sleep cycles from 13-65 hours. Some people are ‘larks’ while others are ‘owls’ . Old people likely to have different sleep cycles (go to sleep early wake up early)
48
Summarise the menstrual cycle
Day 1 bleeding Day 7 oestrogen increases Day 14 ovulation Day 21 progesterone increases Day 28 end of cycle
49
Summarise the stages of sleep (ultradian rhythm)
Stage 1- 5 mins- change from wake to sleep, brainwaves are high frequency- alpha waves Stage 2- 40-50 mins- light sleep- breathing and heart rate slow. spend half your sleep in this stage- alpha waves Stage 3- 4- 15-20 mins- deep sleep moving to very deep sleep. Muscles relax, slow breathing, hard to wake. Waves have lower frequency and higher amplitude. Delta waves (slow wave sleep) Stage 5 (REM)- rapid eye movement. Brain is very active so waves speed up. Dreaming occurs, hear rate and blood pressure increases, sleep paralysis may occur Stage
50
what was McClintocks study into infradian rhythms
had 29 participants with irregular periods 9 of the participants acted as 'donors' and gave pheromone samples everyday by having a cotton pad under their armpit for 8 hours, the other 20 participants would then rub this pheromone on their top lip.
51
what were the findings of McClintocks study into infradian rhythms
68% of women saw a shift in their menstruaol cycles closer to their 'odour donor'
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what did McClintock find about infradian rhythms and university students
those who lived together in un diversity halls tended to synchronise their periods
53
how is seasonal affective disorder an example of infradian rhythm
depressed in winter and not so much in summer Florida- effects 1.4% of population Maine- effects 10% of population correlation with sunlight levels as less light means melatonin secreted for longer which has an effect on melatonin
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what is a strength of infradian rhythms
real world application- SAD led to the establishment of light therapy where a Lightbox is used to reset melatonin levels- Sanassi found this relieved symptoms in 80% of sufferers.
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what are the limitations of infradian rhythms
Confounding variables- McClintock failed to control variables such as diet, stress and exercise which can impact timing of menstrual cycle generalisability- McClintock only studied 29 women poor real world application- Rohan found 46% of people who did light therapy relapsed the next winter compared to 27% of those who did CBT
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what is a strength of ultradian rhythms
real world application- scientists discovered through observing slow wave sleep that it is less common in old age. this is when growth hormone is produced so explains things such as lack of awareness, medication then can be prescribed to treat this.
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what is a limitation of ultradian rhythms
low external validity- research is m mainly done on people sleeping in an unnatural setting or knowing they will be observed, such as Dement and Kleitman's experiment which observed 9 people in a sleep lab using an EEG.
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what are endogenous pacemakers
internal body clocks that maintain many of our biological rhythms
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what are exogenous zeitgebers
external factors which effect our biological rhythms
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what is an example of an endogenous pacemaker
the suprachiasmatic nucleus (SCN)
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what does the SCN do
bundle of nerve cells in hypothalamus maintains sleep/wake cycle as nerve fibres from eye which detect light run just underneath it- SCN receives info about light and influences level of melatonin
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what are two pieces of research into the SCN
DeCoursey's chipmunks Ralph's hamsters
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what was DeCoursey's chipmunk experiment
Destroyed SCN in 30 chipmunks and returned them to wild their sleep wake cycle was completely off and many were killed because of this
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what was Ralph's hamster experiment
bred 'mutant' hamsters with a 20 hour sleep wake cycle SCN cells of mutant hamster put in normal hamster who were then on 20 hour sleep wake cycle
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how is light an example of an EZ
reset the Bodie's main EP the SCN and effects the sleep wake cycle
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what was Campbell and Murphy's experiment into light as an EZ
wanted to see if light could be detected by the without the eyes woke 15 participants up at random times in the night and shone light on the back of their knees there was deviation up to 3 hours of some participants sleep wake cycles
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what are social cues (EZ)
external factors such as meal times and bed times which influence biological rhythms
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what are the limitations of endogenous pacemakers
over simplified- Damiola found that cahnging feeding pattern of mice could alter circadian rhythm of liver by 12 hours while SCN remained the same- shows SCN may not be most important EP animal studies- supported by chipmunks and hamsters. cannot be generalised to humans and ethical issues
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what are the strengths of endogenous pacemakers
sieffre and folkard chipmunks and hamsters
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what are the strengths of exogenous zeitgebers
real world application- research showed that light exposure on people who do East-West flights recover from jet lag- good for economy as persuades more people to fly and people travelling on business can work. more effectively
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what are the different lobes in the brain
frontal parietal temporal occipital
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what is a 'lobe'
a part of an organ that differs from the rest
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describe the somatosensory area
located at the front of the parietal lobes separated from motor area by a 'valley' where sensory information from the skin is represented the amount of the area dedicated to a body part denotes its sensitivity- face and hands take up over half of it
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describe the motor area
back of the frontal lobes controls movements on opposite side of the body damage can lead to loss of fine movements
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describe the visual area
in occipital lobe left gets info from RFV right gets info from LFV damage to this area can result in partial blindness in each eye (dependant on side)
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describe the auditory area
temporal lobes analyses speech based info the more severe the damage the more extensive the loss
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describe the Broca's area
located in left frontal lobe for speech production based off post mortum of Tan (only word he could say) damage leads to Broca's aphasia which is characterised by slow speech that lacks fluency
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describe Wernicke's area
located in left temporal lobe for speech comprehension damage leads to wernicke's aphasia- characterised by fluent speech of nonsense words (neologisms)
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what is contradictory evidence against lateralisation (ao3)
Nielsen analysed brain scans of 1000 people from 7-29 and found that while people did use different hemispheres for different tasks there was no evidence for a stronger side. notion of left brained and right brained people is therefore wrong
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what is supporting research for lateralisation
Luck's research into Michael gazzaniga found that people with split brains were better at things such as identifying an odd one out. supports Kingstone's idea that the LH's better cognitive strategies are 'watered down' by the RH rogers chickens
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what is the definition of plasticity
the idea that the brain has the ability to change throughout life.
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what did Gopnick find
number of synapses per neutron peaks at 15,000 at 2-3 years old- twice as many in the adult brain.
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what is synaptic pruning
when unused synaptic connections are deleted while frequently used ones are strengthened. this is how plasticity works
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what are two studies that support plasticity
Maguire draganski
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what is functional recovery
when the brain recovers from trauma by other areas of the brain taking up the functions of damaged areas. this can happen rapidly (spontaneous recovery) before slowing down over the next few weeks and months when therapy may be needed for further improvement.
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what is the evaluation for plasticity
bezzola bi-lingual
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what is the evaluation for functional recovery
constraint therapy school jody
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what is contrasting evidence for exogenous zeitgebers (AO3)
blind man with 24.9 hour sleep wake cycle was exposed to cues such as regular mealtimes and waking times etc but this did not fix the cycle inuits in the artic circle maintain regular sleep wake cycles despite spending six months in total darkness
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what are newborn babies sleep wake cycles
random
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when do babies develop circadian rhythms
around 6 weeks
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what are babies biological rhythms like by 16 weeks
depends on the schedules imposed by the parents- meal times and bed times etc
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what role does the pineal gland play in secretion of melatonin
the SCN passes information it receives on day length and light to the pineal gland. pineal gland then increases or decreases production of melatonin
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describe the SCN
tiny bundle of nerves in hypothalamus in each hemisphere nerve fibres connected to the eye cross in the optic chiasm the SCN lies just above the optic chiasm and receives info from this structure about light levels continues to work even when eyes are closed
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