AAW - Drug suffixes

Question 1

-azole

Answer 1

Ergosterol synthesis inhibitor

e.g. ketoconazole

Question 2

-bendazole

Answer 2

antiparasitic/anthelmintic

e.g. Mebendazole

Question 3

-cillin

Answer 3

Peptidoglycan synthesis inhibitor

e.g. Ampicillin

Question 4

-cycline

Answer 4

protein synthesis inhibitor

e.g. Tetracycline (this binds 30s)

Question 5

-mivir

Answer 5

Neuraminidase inhibitor

e.g. Oseltamivir

Question 6

-navir

Answer 6

Protease inhibitor

e.g. Ritonavir (this one also inhibits P450)

NAVIR TEASE a proTEASE

Question 7

-ovir

Answer 7

DNA polymerase inhibitor

e.g. Acyclovir (used to treat viruses mainly herpes class)

Question 8

-thromycin

Answer 8

Macrolide

e.g. Azithromycin, Erythromycin

ALSO fidaxomycin

Question 9

-ane

Answer 9

Inhalational general anesthetic

e.g. Halothane

Question 10

-azine

Answer 10

Typical antipsychotic

e.g. Thioridazine

and haldol

Question 11

-barbital

Answer 11

Barbiturate

e.g. phenobarbital

Question 12

-caine

Answer 12

Local anesthetic

e.g. Lidocaine

Question 13

-etine

Answer 13

SSRI

e.g. Fluoxetine

Question 14

-ipramine

Answer 14

TCA

e.g. Imipramine, Desipramine

“I’M DES, your Traumatic Care Attendant”

Question 15

-triptan

Answer 15

Serotonin 1B/1D agonist

Sumatriptan (constricts vessels in brain for migraine and reduces trigeminal nerve firings for cluster headaches)

Question 16

-triptyline

Answer 16

also a TCA

e.g. Amitriptyline

“DES is clumsy and trips alot”

Question 17

-zepam

Answer 17

Benzodiazepine

e.g. Diazepam

Question 18

-zolam

Answer 18

Benzodiazepine

e.g. Alprazolam

Question 19

-chol

Answer 19

Cholinergic agonist

e.g. Bethanechol/carbachol (selectively stimulates muscarinic receptors without any effect on nicotinic receptors, can make you pee)

Question 20

• curium

- curonium

Answer 20

Non-depolarizing paralytic

e.g. Atracurium or Vecuronium, Rocuronium

Question 21

-olol

Answer 21

Beta-blocker

e.g. Propanolol

Question 22

-stigmine

Answer 22

AChE inhibitor

e.g. Neostigmine

Question 23

-terol

Answer 23

Beta2-agonist

Albuterol (short), Salmeterol, Formeterol (long)

Question 24

-zosin

Answer 24

Alpha1-antagonist

e.g. Prazosin

Question 25

-afil

Answer 25

PDE-5 inhibitor e.g. Slidenafil

Question 26

-dipine

Answer 26

Dihydropyridine calcium clannel blocker e.g. Amlodipine

Question 27

-pril

Answer 27

ACE inhibitor e.g. Catropril

Question 28

-sartan

Answer 28

Angiotensin-II receptor blocker e.g. Losartan

Question 29

-statin

Answer 29

HMG-CoA reductase inhibitor e.g. Atorvastatin

Question 30

-dronate

Answer 30

Bisphosphonate (used to treat osteoporosis) e.g. Alendronate

Question 31

-glitazone

Answer 31

PPAR-gamma activator (binds PPAR receptors on fat cells and making them more sensitive to insulin) e.g. Rosiglitazone

Question 32

-prazole

Answer 32

Proton pump inhibitor - treats GERD e.g. Omeprazole

Question 33

-prost

Answer 33

Prostaglandin analog e.g. Latanoprost

Question 34

-tidine

Answer 34

H2-antagonist - inhibits stomach acid production e.g. Cimetidine

Question 35

-tropin

Answer 35

Pituitary hormone e.g. Somatotropin

Question 36

-ximab

Answer 36

Chimeric monoclonal Ab e.g. Basiliximab

Question 37

-zumab

Answer 37

Humanized monoclonal Ab e.g. Daclizumab