ABX Flashcards

(70 cards)

1
Q

Broad spectrum PCN

A

Ampicillin

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2
Q

Interesting SE of ampicillin

A

Black tongue (thrush)

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3
Q

How is Ampicillin taken?

A

Empty stomach w/ water

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4
Q

Important Rx interactions w/ ampicillin?

A

Tetracycline - decreases the effectiveness

Allopurinol/Probencid - decreases elimination AND increases concentraion (effectiveness)

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5
Q

Which PCN combo is taken PO?

A

Amoxicillin/Clavulante

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6
Q

How is cefalozin taken?

A

With food

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7
Q

Purpose of cefalozin?

A

Presurgery Prophylaxis

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8
Q

Important Rx interactions w/ cefalozin?

A

Vancomycin and Aminoglycosides

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9
Q

What are alternatives to PCN allergies?

A

Impenem-Cilastatin
Vancomycin (PCN resistant)
Erythromycin

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10
Q

What class is cefalozin?

A

Cephalosporin

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11
Q

What class is Impenem-Cilastatin?

A

Carbapenems

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12
Q

Which Rx affect Liver Fx?

A

Impenem-Cilastatin

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13
Q

What class is Aztreonam?

A

Monobactams

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14
Q

Does Aztreonam work on GN or GP organisms?

A

GN and gentler on NF

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15
Q

Important Rx interactions w/ Aztreonam?

A

Aminoglycosides (Renal)

Furesemide (INC conc/effectiveness)

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16
Q

What class is gentamicin?

A

Aminoglycosides

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17
Q

Purpose of prescribing gentamicin?

A

Serious GN or anaerobic infections

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18
Q

Important gentamicin SE?

A

Ototoxic (permanent)

Nephrotoxic

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19
Q

Important RX interactions w/ gentamicin?

A

If combo w/ PCN - decrease dose
Vancomycin
Amphotercin B
Loop Diuretics

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20
Q

What class is Ciprofloxacin?

A

FLQ

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21
Q

What class is tetracycline hydrochloride?

A

Tetracyclines

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22
Q

What class is TMP-SMX?

A

Sulfonamides

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23
Q

What Rx is for anthrax infections/prophylaxis?

A

Ciprofloxacin

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24
Q

What Rx is associated with tendonitis/Achilles tendon rupture?

A

Ciprofloxacin

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25
What Rx is associated with tooth discoloration?
Tetracycline hydrochloride | CI <8yo and PREG
26
What Rx is preferred for Pneumocystis Jiroveci (HIV inf)?
TMP-SMX
27
What medications are preferred for UTI's?
TMP-SMX | Nitrofurantoin
28
What medications are CI for PEDS?
Ciprofloxacin (Not 1st L) TMP-SMX (<2mo - kernictus) Tetracycline Hydrochloride (Tooth discoloration)
29
What Rx prolongs QT Interval?
Ciprofloxacin
30
What Rx if combined w/ another Rx requires ACHS?
TMP-SMX and Sulfonylureas
31
What Rx is used to TXT uncomplicated UTI or prophylaxis for UTI's?
Nitrofurantoin
32
Which Rx is not ABX and is used for UTI pain relief?
Phenazopyridine
33
What Rx is bacterial static?
Erythromycin
34
What Rx is used for STI eye infections in newborns as an ointment?
Erythromycin
35
What is erythromycin combined w/ to increase ability?
Streptomicin
36
What Rx is ototoxic?
Gentamicin (IRREV) Erythromycin (REV) Vancomycin
37
What Rx is associated with crystal build up and requires 1.5-3L of fluid?
TMP-SMX
38
What is an important SE of TMP-SMX?
SJS
39
What is an important SE of nitrofurantoin?
EKG - BBB - Wide QRS and ventricle issues
40
What Rx decreases WBC/PLT?
Phenazopyririnde
41
How is erythromycin taken?
Empty stomach with water
42
What is an important RX combination that could cause cardiac arrest?
Erythromycin and Diltizam or Fluconazole
43
What Rx is associated w/ disulfram reaction (ETOH)?
Metronidazole
44
What Rx combination is associated with serotonin syndrome?
Linezolid - SSRI's - MAOI's - TCA's
45
What Rx is a first line C-Diff TXT?
Metronidazole - (1 dose prophylaxis if abdominal surgery occurs quickly)
46
What Rx is extrapyridimal SE's?
Metronidazole
47
What Rx can cause redman syndrome?
Vancomycin
48
What Rx can treat MRSA/VRE?
Linezolid
49
What Rx combination can be used for C-Diff?
Metronidazole (IV) and Vancomycin (PO)
50
What Rx can cause bone marrow suppression?
Linezolid
51
What Rx is for nonresistant and active TB infections only?
Rifampin
52
What Rx changes the colors of various body fluids?
Rifampin - Harmless
53
What Rx can cause optic neuritis?
Ethambutol - visual acuity monitoring
54
Which TB Rx is not hepatotoxic?
Ethambutol
55
What TB Rx should be taken with vitamins?
Isoniazid - B6
56
Which TB Rx causes a increasingly efficient liver?
Rifampin
57
Do not give these RXN for PCN allergies...
PCN, Cephalosporins, and Carbapenems
58
What monobactam is not cross sensitive with PCN?
Aztreonam
59
S/S and Steven Johnson syndrome (SJS)?
Malaise, low fever | Rash to Slough
60
What are S/S of redman syndrome?
Flush, HOTN Rash GIve >=60m diluted
61
Four 1st line TB Rx?
Isoniazid Rifampin Pyrazinamide Ethanbutol
62
Four 2nd line TB Rx?
Levofloxacin (FLQ) Moxifloxacin (FLQ) Amikacin (Aminoglycoside) Streptomycin (Macrolide)
63
TXT recommendation for latent TB infection?
TXT - 1 Rx for 9mo OR 2 Rx for 3mo
64
TXT recommendation for active TB infection?
TXT - 4 Rx for 2mo OR 2 Rx for 4mo
65
Rx affecting liver Fx
Carbapenems, Erythromycin, Isoniazid, Rifampin, Pyrazinamide
66
How to monitor LFTs?
Liver enzymes, TP, albumin, bilirubin
67
How to monitor Renal Fx?
Titrate - Check I/O - labs (Cr/BUN/SG) - Fluids
68
Rx causing C-Diff or yeast infections?
PCN, Cephs, Aztreonam, Tertacycline Hydrochloride, Erythromycin,
69
Rx that interact w/ metalllics?
Ciprofloxacin, Tertacycline Hydrochloride, Erythromycin
70
Rx that cause photosensitivity?
TMP-SMX, Tertacycline Hydrochloride, Ciprofloxacin