Acute and Emergency Dermatology Flashcards Preview

10. Dermatology > Acute and Emergency Dermatology > Flashcards

Flashcards in Acute and Emergency Dermatology Deck (22)
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1

List the 9 types of drug reaction.

Maculopapular/morbilliform
Papulosquamous
Photo-toxic
Pustular
Lichenoid
Fixed drug rash
Psoriasiform rash
Bullous rash
Itch (with no rash)

2

List 6 types of drug which commonly cause drug reactions.

Antibiotics
NSAIDs
Chemotherapy agents
Psychotropic drugs
Anti-epileptic drugs
Cardiac drugs

3

List 6 common causes of urticaria.

Unknown
Viral infections
Drug induced
Foods
Parasitic infections
Physical stimulants

4

How would you treat urticaria? (4)

Antihistamines
Steroids
Immunosuppression
Omiluzimab

5

List 3 causes of erythema multiforme.

Herpes simplex
Epstein Barr virus
Drug reaction

6

What causes Ritter's disease?

What is it also known by?

How do you treat it? (2)

Staphylococcal infection

Staphylococcal scalded skin syndrome (SSSS)

TREATMENT:
IV antibiotics
Supportive treatment

7

List 3 causes of vaculitis.

Polyarteritis nodosa
Acute nephritis
Serum sickness

8

List 5 causes of erythroderma.

Psoriasis
Eczema
Drug reactions
Cutaneous lymphoma
Others

9

How would you treat erythroderma? (2)

Treat underlying skin disorder
Supportive treatment

10

List 2 causes of toxic epidermal necrolysis (TEN).

Drug induced
Genetic predisposition to reacting to certain drugs

11

What does TEN stand for?

Toxic epidermal necrolysis

12

Describe the clinical features of TEN. (9)

Preceding flu-like illness

Red, painful skin rash
-Macules
-Diffuse erythema
-Target lesions
-Flaccid blisters
-Conversion of blisters into large sheets of peeling skin
-Exposure of dermis
-Nikolsky sign positive

Other organ involvement

13

How would you manage TEN? (4)

Stop causative drug
Supportive treatment
Appropriate dressings
Immunosuppression (rare)

14

Define "bullous pemphigoid"

A chronic, itchy, blistering autoimmune skin condition most common in the elderly; blisters most commonly occur on the limbs and may last for several days

15

Describe the clinical features of bullous pemphigoid. Consider:

a) Features of rash (4)
b) Distribution (4)

RED, ITCHY RASH:
-Large, itchy blisters (up to 5cm diameter)
-Fluid-filled (clear, cloudy or blood-stained)
-Tense (i.e. skin is stretched taut)
-Non-scarring

DISTRIBUTION:
Upper arms
Thighs
Body folds
Abdomen

16

How would you treat bullous pemphigoid? (3)

What is the prognosis?

Steroids
Immunosuppression
Antibiotics

Treatment is NOT curative; but controls symptoms until disease disappears on its own

17

Define "bullous pemphigus".

A rare but serious autoimmune disease marked by successive outbreaks of blisters; the blisters are superficial and do not remain intact for long

18

Describe the clinical features of bullous pemphigus. (4)

Painful

Fragile blisters (burst easily)
-Exposes unhealed skin

Non-scarring

Relapsing and remitting disease

19

How would you manage bullous pemphigus? (3)

What is the prognosis?

Steroids
Immunosuppression
Antibiotics

Disease will NOT go away (unlike pemphigoid), but treatment can control symptoms

20

Define "dermatitis herpetiformis".

An uncommon, extremely itchy rash with symmetrical blistering, especially on the knees, elbows, buttocks and shoulders; associated with gluten sensitivity

21

What causes dermatitis herpetiformis?

Coeliac disease

22

How would you manage dermatitis herpetiformis? (2)

Dapsone (antibiotic)
Gluten free diet