Flashcards in Acute and Emergency Dermatology Deck (22)
List the 9 types of drug reaction.
Fixed drug rash
Itch (with no rash)
List 6 types of drug which commonly cause drug reactions.
List 6 common causes of urticaria.
How would you treat urticaria? (4)
List 3 causes of erythema multiforme.
Epstein Barr virus
What causes Ritter's disease?
What is it also known by?
How do you treat it? (2)
Staphylococcal scalded skin syndrome (SSSS)
List 3 causes of vaculitis.
List 5 causes of erythroderma.
How would you treat erythroderma? (2)
Treat underlying skin disorder
List 2 causes of toxic epidermal necrolysis (TEN).
Genetic predisposition to reacting to certain drugs
What does TEN stand for?
Toxic epidermal necrolysis
Describe the clinical features of TEN. (9)
Preceding flu-like illness
Red, painful skin rash
-Conversion of blisters into large sheets of peeling skin
-Exposure of dermis
-Nikolsky sign positive
Other organ involvement
How would you manage TEN? (4)
Stop causative drug
Define "bullous pemphigoid"
A chronic, itchy, blistering autoimmune skin condition most common in the elderly; blisters most commonly occur on the limbs and may last for several days
Describe the clinical features of bullous pemphigoid. Consider:
a) Features of rash (4)
b) Distribution (4)
RED, ITCHY RASH:
-Large, itchy blisters (up to 5cm diameter)
-Fluid-filled (clear, cloudy or blood-stained)
-Tense (i.e. skin is stretched taut)
How would you treat bullous pemphigoid? (3)
What is the prognosis?
Treatment is NOT curative; but controls symptoms until disease disappears on its own
Define "bullous pemphigus".
A rare but serious autoimmune disease marked by successive outbreaks of blisters; the blisters are superficial and do not remain intact for long
Describe the clinical features of bullous pemphigus. (4)
Fragile blisters (burst easily)
-Exposes unhealed skin
Relapsing and remitting disease
How would you manage bullous pemphigus? (3)
What is the prognosis?
Disease will NOT go away (unlike pemphigoid), but treatment can control symptoms
Define "dermatitis herpetiformis".
An uncommon, extremely itchy rash with symmetrical blistering, especially on the knees, elbows, buttocks and shoulders; associated with gluten sensitivity
What causes dermatitis herpetiformis?