Flashcards in Acute/Emergency Dermatology Deck (10):
What is erythroderma and what can cause it? How is it treated?
Inflammation on >90% of skin
Removal of cause
Fluid balance and nutrition
Emollients, oral/eye care
How does Stevens-Johnson syndrome present? What can cause it?
Fever, malaise, arthralgia
Target lesions, blisters
Erosions <10% of surface
Cause by - antibiotics, anticonvulsants, allopurinol, NSAIDs
How does Toxic epidermal necrolysis present?
Prodromal febrile illness
Mucous membrane ulceration
Becomes confluent, sloughing (30% desquamation)
Causes are same as SJS
What is erythema multiforme? What can cause it?
Abrupt onset of 100s of lesions over 24 hours
- distal > proximal
- palms and soles
- mucosal surfaces
Hypersensitivity, usually to infection
Usually self-limiting - symptomatic/causative treatment
What is DRESS? What can cause it?
Drug rash with eosinophilia and systemic symptoms syndrome
Fever and widespread rash
Up to 10% mortality
2-8 weeks after drug exposure
Consider systemic steroids/immunosuppression
What is the difference between pemphigus and pemphigoid? How are they treated?
Pemphigus blisters are fragile - not usually seen intact
- affects desmosomes
- systemic steroids, supportive therapies
Pemphigoid blisters usually intact
- affects dermo-epidermal junction
- topical steroids (systemic if diffuse)
Pemphigoid more common
What are the features of erythrodermic/pustular psoriasis? What causes it and how is it treated?
Rapid generalised erythema +/- pustule clusters
Fever, elevated WCC
Can be caused by infection or sudden steroid withdrawal
Treat with bland emollient
Often requires systemic therapy
How does eczema present? What causes it and how is it treated?
Monomorphic blisters and punched out erosions
- generally painful, not itchy
Fever and lethargy
Disseminated HSV on background of poorly controlled eczema
Treated with aciclovir
Mild topical steroid for eczema
Treat secondary infection
What is staphylococcal scalded skin syndrome? How is it treated?
Diffuse erythematous rash with skin tenderness
More prominent in flexures
Blistering and desquamation follows
Fever and irritability
Can be caused by staph, immunocompromised
- IV antibiotics, supportive care