Adam Revision Flashcards

1
Q

4 stages glucose metabolism

A

Glycolysis
Acetyl CoA formation
Krebs cycle
ETC

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2
Q

How many ATP generated from glycolysis

A

4

2 net

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3
Q

How many ATP generated by Acetyl CoA formation

A

None

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4
Q

How many ATP made in Krebs cycle

A

2

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5
Q

How many ATP made in ETC

A

34

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6
Q

How many ATP made from glucose metabolism in total

A

38

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7
Q

Enzymes only do 1 thing at a time yes or no

A

Yes

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8
Q

Glycolysis what do you start with

What do you want to finish with

A

Glucose - 6 carbon molecule

2 pyruvates, 3 carbon molecules

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9
Q

Acetyl CoAformation start and finish with

A

2 x pyruvates 3 carbons each

2 Acetyl CoA 2 carbons each

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10
Q

How many times does Krebs cycle turn for each molecule Glucose

A

Twice - 1 for each Acetyl CoA

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11
Q

What does 2c Acetyl CoA need to become at start of Krebs and how

A

6 carbon Citrate

Via combining with 4 carbon oxaloacetate

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12
Q

How many ATP
NADH
FADH2 made in Krebs

A

2 ATP
6 NADH
2 FADH2

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13
Q
How many
ATP
NADH
FADH2 
Made in Acetyl CoA formation
A

2 ATP
2 NADH
0 fadh2

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14
Q

How many
ATP
NADH
Fadh2

Made in glycolysis

A

2, 2 & 2

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15
Q

Where are the 5 enzymes located that are in the ETC

A

Inner mitochondrial membrane

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16
Q

In ETC hydrogen ions also called

A

Protons

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17
Q

In ETC protons are pumped via NADH & FADH2 where

A

Inter-membrane space

Increases the acidity and creates a gradient

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18
Q

H+ ions will always move

A

Down their concentration gradient

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19
Q

5th enzyme in ETC called

A

ATP synthase

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20
Q

In ETC every NADH makes - ATP

21
Q

In ETC every FADH2 makes - ATP

22
Q

How many NADH in ETC = how many ATP

A

10 NADH = 30 ATP

23
Q

How many FADH2 in ETC = how many ATP

A

2 FADH2 = 4 ATP

24
Q

How is total of 38 ATP derived in glycolysis

A
10 NADH in ETC = 30
2 FADH2 in ETC = 4
2 ATP in Glycolysis 
2 ATP in Acetyl CoA formation
= 38 ATP
25
What process replaces glycolysis in fat metabolism
Beta oxidation
26
What is a phosphorylation reaction
An exchange of phosphate groups | Either gaining or losing
27
Kinase always means a what
Phosphorylation reaction - so ATP or ADP is present somewhere
28
What allows sugar into cells
Glucose 4 transporters
29
How do you make citrate in citric acid cycle
Bind Acetyl CoA with oxaloacetate
30
How does Krebs cycle affect no of carbons that make up molecules in it
Reduces the carbons from 6 (citrate)round to 4 (oxaloacetate) over and over - Acetyl CoA at beginning to start it all off again and make citrate
31
8 molecules in Krebs cycle
``` Oxaloacetate Citrate Isocitrate Alpha-ketogluterate Succinyl CoA Succinate Fumerate Malate ``` Oxaloacetate
32
How many turns of Krebs for 1 glucose molecule
Twice - 1 for each Acetyl CoA
33
`where is FADH2 in krebs cycle
succinate>fumerate
34
where are 3 NADH in krebs
isocitrate>ketoglutinate alpha-ketoglutinate> Succinyl coA Malate > oxaloacetate
35
how many NADH made in krebs for each glucose molecule
6
36
how many FADH2 made in krebs for each glucose molecule
2
37
how many ATP made in krebs from each glucose molecule
2
38
how many NADH made in krebs for each Acetyl CoA
3
39
How many FADH2 in krebs for each Acetyl CoA
1
40
How many ATP made in krebs for each Acetyl CoA
1
41
which is the 5th and most important enzyme in ETC
ATP synthase
42
what role to NADH and FADH play in ETC
electron donors
43
what happens to NADH & FADH2 as they pass through ETC
get reduced - lose H+ ions
44
where do the H+ ions go as they are released through the ETC
into inter-membrane space
45
what happens in the inter0membrane space as ETC progresses
space becomes acidic and creates a gradient
46
how is ATP made via ATP synthase
via oxidative phosphorylation | binds with ADP & free phosphate after passing through ATP synthase
47
where does ETC occur
in mitochondrial matrix
48
what does pyruvate depend on to get into mitochondria
02