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Flashcards in Addiction Deck (28):
1

How is alcoholic hallucinosis different from normal auditory and tactile hallucinations?

Patients are usually aware that hallucinations aren't real

2

A patient presents belligerent, paranoid, violent and hostile. He has slurred speech and vertical nystagmus. this is ...

PCP intoxication

3

What is the best treatment for someone with PCP intoxication?

don't restrain, don't give benzos except for muscle spasms and only if necessary (could slow down excretion), don't give antipsychotic. hang low, maybe give antihypertensive

4

What triad of symptoms would indicate PCP intoxication?

nystagmus, muscle rigidity, cannabinoids in urine

5

What are the criteria for substance abuse?

Work affected
Interpersonal relationships
Legal issues
Dangerous situations

6

When do signs and symptoms of alcohol withdrawal begin?

6-24 hours after last drink

7

When do delirium tremens begin? What do they look like?

48-72 hours - hallucinations, autonomic instability,

8

What are the characteristics of Korsakoff's psychosis?

confabulations - false memories

9

What BAL is associated with intoxication?

150

10

What medications exist for alcohol dependence and how do they work?

antabuse (disulfuram) - blocks alcohol dehydrogenase
naltrexone - opioid receptor blocker, prevents high
Acamprosate - inhibits glutamatergic
Topiramate - anticonvulsant that potentiates GABA

11

What is the mechanism of cocaine?

blocks dopamine reuptake

12

How long do the withdrawal symptoms of cocaine last?

18 hours, give or take

13

What are the consequences of chronic amphetamine use?

acne, dental problems

14

What is a good treatment for benzo overdose?

flumazenil - short acting antagonist

15

What is date rape drug?

GHB - depressant that causes memory loss

16

What are the symptoms associated with opioid intoxication?

sedation, constricted pupils, respiratory depression

17

What opioid drug actually produces dilation?

demerol dilates

18

What are the symptoms associated with opioid withdrawal?

dysphoria, insomnia, lacrimation, rhinorrhea, sweating, dilated pupils, hypertension

19

What treatments exists for opiod dependence?

methadone, suboxone (partial opioid agonist), naltrexone (competitive antagonist)

20

Can people who take hallucinogens go through a withdrawal?

not really, but can have flashbacks

21

What is the mechanism of marijuana?

inhibits adenylate cyclase

22

How frequently does marijuana dependence occur?

5% of the time

23

What is the mechanism of inhalants?

CNS depressent

24

What are the potential consequences of inhalant overdose?

respiratory depression, cardiac arrhythmia, permanent damage to CNS

25

What is the mechanism of caffeine?

adenosine antagonist

26

How long do caffeine withdrawal symptoms usually last?

1 week

27

What are the therapies currently available for nicotine dependence?

Chantix - nicotinic receptor agonist
Zyban - antidepressant that helps reduce withdrawal
Nicotine replacement therapy
Behavioral counseling

28

What is the mortality rate of DT if untreated?

30%